FIGURE 103-1. Adrenal steroidogenesis. Biosynthetic pathways from cholesterol to mineralocorticoids (aldosterone), glucocorticoids (cortisol), and androgens (androstenedione) are shown and the cellular locations of enzyme activities indicated. CMO, Corticosterone methyl oxidase;…
FIGURE 125-1. Photomicrograph of an adult primate ovary showing the follicular and luteal units in the cortex and large blood vessels and nerves in the medulla. Gf, Graafian follicle; pf,…
FIGURE 76-1. Regulation of thyroid hormone production in the hypothalamic-pituitary axis. Thyroid hormone is produced in the thyroid gland under control of thyroid-stimulating hormone (TSH). Circulating hormones exert multiple effects…
FIGURE 37-1. Obesity and adipocyte hypertrophy. Adipocyte hypertrophy is a key feature of the insulin-resistant state. The flux of free fatty acids out of adipose tissue is disordered in obesity,…
FIGURE 113-1. Effects of gravity on arterial and venous blood pressures in an erect, motionless man. Arterial and venous pressures in the lower part of the body are increased, and…
FIGURE 54-1. Electron microscopic photomicrographs. A, Normal glomerular basement membrane (GBM) on the left compared to thickened GBM from a proteinuric type 1 diabetic patient on the right. B, Normal…
FIGURE 150-1. Schematic representation of the distribution of 384 multiple endocrine neoplasia type 1 (MEN1) tumors in 220 patients with MEN1. The proportions of patients in whom parathyroid, pancreatic, or…
FIGURE 93-1. Estimated proportional carriage of thyroxine (T4) on the three major plasma binding proteins is shown for euthyroid subjects with normal or variant T4 binding proteins. In the face…
FIGURE 119-1. The three stages of normal sexual differentiation. 1, Chromosomal sex is determined by the sex chromosome (X or Y) present in the spermatozoon at fertilization. 2, Gonadal sex…
FIGURE 120-1. Timeline of changes in the reproductive axis. As puberty progresses, there is little change in the frequency of LH pulsations. However, the mass of hormone secreted during each…
