FIGURE 32-1 Amino acid sequence of human and hagfish insulins, with substitutions occurring at each position in 70 other known vertebrate insulins shown below for comparison. Invariant residues are enclosed…
Hypervitaminosis can occur when pharmaceutical vitamin D is taken in excess, with a wide variety of symptoms and signs related to hypercalciuria, hypercalcemia, and metastatic calcifications (Table 58-2). The toxic…
Management of young children with diabetes, especially those younger than 5 years old, must balance opposing risks of hypoglycemia (see section on Hypoglycemia below) and future vascular complications. The relative…
Technetium-99m (99mTc) in the form of pertechnetate is trapped by the thyroid gland and other sites that concentrate iodide (salivary glands, gastric mucosa), but it is not organified in the…
FIGURE 63-1. Bone biopsy photomicrographs. A, Local osteolytic hypercalcemia secondary to leukemia. Note the presence of leukemic cells in the marrow space and numerous osteoclasts lining the trabecular surface. B,…
FIGURE 65-1. Urinary cyclic adenosine monophosphate (cAMP) excretion in response to an infusion of bovine parathyroid extract (300 USP units). The peak response in normal subjects () and those with…
FIGURE 64-1. Flow diagram for localization strategy in previously unoperated patients. US, Ultrasound. FIGURE 64-2. A, Sestamibi scan showing uptake in thyroid as well as parathyroid tissue. B, Thyroid uptake…
FIGURE 123-1. Mammary gland of human female at birth formed by several excretory ducts, ending in terminal ducts. A, Detail of the inset showing the club-shaped terminal end bud from…
FIGURE 145-1. Cartoon illustrating the cascade on transcription factor genes programming hypothalamic and pituitary embryogenesis and function. Most of this information was derived from genetic studies in mice. The list…
FIGURE 13-1. Standard mortality rates (SMR) and 95% confidence intervals (CI) in individual studies on patients with nonmalignant pituitary diseases not associated with excess adrenocorticotropic hormone (ACTH) or growth hormone…
