HEMATOLOGY

Infectious Processes in Blood and Bone Marrow

Apr 3, 2021 by in HEMATOLOGY Comments Off on Infectious Processes in Blood and Bone Marrow

Viral Infections Certain viral infections can cause cytopathic changes in blood cells or changes in the maturation of blood cells. The nuclear or cytoplasmic inclusions of some viruses, particularly the…

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B-Cell Chronic Lymphoid Leukemias

Apr 3, 2021 by in HEMATOLOGY Comments Off on B-Cell Chronic Lymphoid Leukemias

In healthy adults and older children, the majority of circulating lymphocytes in the blood are T cells (approximately 70% of lymphocytes) with fewer B cells (25%) and natural killer (NK)…

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Indolent and Aggressive B-Cell Lymphoma

Apr 3, 2021 by in HEMATOLOGY Comments Off on Indolent and Aggressive B-Cell Lymphoma

Introduction Non-Hodgkin B-cell lymphomas are the seventh most common malignant neoplasm and account for approximately 4% of all cancers, according to the American Cancer Society, with approximately 77,000 cases anticipated…

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Transfusion Medicine and Cellular Therapy

Apr 3, 2021 by in HEMATOLOGY Comments Off on Transfusion Medicine and Cellular Therapy

Blood Collection In the United States, 14.2 million red blood cells and whole blood donations and approximately 2.4 million apheresis and whole blood–derived platelets were collected in 2013. Although whole…

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Childhood Hematopoietic Disorders

Apr 3, 2021 by in HEMATOLOGY Comments Off on Childhood Hematopoietic Disorders

General Overview and Incidence Pediatric hematology/hematopathology spans the spectrum of benign, malignant, and neoplastic mimickers. Neoplastic lymphoid, myeloid, and histocytic neoplasms follow criteria in the updated World Health Organization (WHO)…

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Posttransplant Lymphoproliferative Disorders and Immunodeficiency

Apr 3, 2021 by in HEMATOLOGY Comments Off on Posttransplant Lymphoproliferative Disorders and Immunodeficiency

General Overview and Incidence Incidence varies depending on the institution, patient population, allograph types, and immunosuppression regimes. Etiology/Histopathology Clinical settings causing immune dysfunctions, such as viral Epstein-Barr virus (EBV) infection,…

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Hemophilia

Apr 3, 2021 by in HEMATOLOGY Comments Off on Hemophilia

General Overview and Incidence Overview of Hemophilia The hemophilias are bleeding disorders caused by the absence or decrease of factor VIII in hemophilia A or factor IX in hemophilia B….

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Myeloma and Related Conditions

Apr 3, 2021 by in HEMATOLOGY Comments Off on Myeloma and Related Conditions

General Overview and Incidence Multiple myeloma (MM) is a malignancy of clonal plasma cells and is part of a spectrum of plasma cells disorders encompassing the benign asymptomatic condition monoclonal…

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Precursor Lymphoid Neoplasms

Apr 3, 2021 by in HEMATOLOGY Comments Off on Precursor Lymphoid Neoplasms

General Overview and Incidence Precursor lymphoid neoplasms or acute lymphoblastic leukemia (ALL) is the second most common leukemia affecting adults with about 1.6 per 100,000 and 6500 cases per year…

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