HEMATOLOGY

Imaging in the Evaluation and Management of Childhood Cancer

Apr 1, 2019 by in HEMATOLOGY Comments Off on Imaging in the Evaluation and Management of Childhood Cancer

Chapter Outline TECHNICAL CONSIDERATIONS Conventional Radiography Ultrasound Computed Tomography Magnetic Resonance Imaging Nuclear Medicine STAGING CONSIDERATIONS CENTRAL NERVOUS SYSTEM TUMORS Supratentorial Tumors Midline Supratentorial Tumors Infratentorial Tumors PULMONARY AND INTRATHORACIC…

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Tumors of the Brain and Spinal Cord

Apr 1, 2019 by in HEMATOLOGY Comments Off on Tumors of the Brain and Spinal Cord

Chapter Outline EPIDEMIOLOGY NEURODEVELOPMENT Neural Tube Development of Brain Structures Cancer Stem Cells Genetic and Signaling Pathways Implicated in Development and in Pediatric Tumors CONCEPTUAL ORGANIZATION OF PEDIATRIC BRAIN TUMORS…

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Nonrhabdomyosarcoma Soft Tissue Sarcomas and Other Soft Tissue Tumors

Apr 1, 2019 by in HEMATOLOGY Comments Off on Nonrhabdomyosarcoma Soft Tissue Sarcomas and Other Soft Tissue Tumors

Chapter Outline EPIDEMIOLOGY PRESENTATION AND EVALUATION STAGING AND GRADING TREATMENT Local Control Chemotherapy GENERAL BIOLOGIC FEATURES ADIPOCYTIC TUMORS FIBROBLASTIC AND MYOFIBROBLASTIC TUMORS Desmoid Tumor Infantile Myofibroma/Myofibromatosis and Hemangiopericytoma Infantile Fibrosarcoma…

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Cytogenetic and Molecular Pathology of Pediatric Cancer

Apr 1, 2019 by in HEMATOLOGY Comments Off on Cytogenetic and Molecular Pathology of Pediatric Cancer

Chapter Outline CYTOGENETIC AND MOLECULAR METHODOLOGIES Karyotyping Molecular Cytogenetics Polymerase Chain Reaction–Based Molecular Assays Array Comparative Genomic Hybridization and Single Nucleotide Polymorphism Profiling Assays Next-Generation Sequencing and Other Techniques GENOMIC…

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Pediatric Germ Cell Tumors

Apr 1, 2019 by in HEMATOLOGY Comments Off on Pediatric Germ Cell Tumors

Chapter Outline DEVELOPMENT OF THE GERMLINE Specification of Primordial Germ Cells Primordial Germ Cell Migration Erasure of Imprinting Gonadogenesis HISTOPATHOLOGY OF GERM CELL TUMORS Overview of Testicular Germ Cell Tumors…

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Rare Tumors of Childhood

Apr 1, 2019 by in HEMATOLOGY Comments Off on Rare Tumors of Childhood

Chapter Outline OROPHARYNGEAL CANCER NASOPHARYNGEAL CARCINOMA Epidemiology Presentation Staging and Evaluation Treatment THYROID CARCINOMA Epidemiology Pathology and Molecular Pathology Clinical Presentation and Staging Treatment and Outcome BREAST TUMORS PULMONARY TUMORS…

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Oncologic Emergencies

Apr 1, 2019 by in HEMATOLOGY Comments Off on Oncologic Emergencies

Chapter Outline ANTERIOR MEDIASTINAL MASSES Definition Clinical Presentation Evaluation and Imaging Treatment Conclusions SPINAL CORD COMPRESSION Clinical Presentation Evaluation and Imaging Treatment Late Effects HYPERLEUKOCYTOSIS AND LEUKOSTASIS Definition Pathogenesis Clinical…

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Osteosarcoma

Apr 1, 2019 by in HEMATOLOGY Comments Off on Osteosarcoma

Chapter Outline EPIDEMIOLOGY ETIOLOGY CLINICAL PRESENTATION AND EVALUATION Clinical Manifestations Radiologic Evaluation Biopsy Laboratory Evaluation PATHOLOGY AND STAGING Pathology Staging NATURAL HISTORY AND PROGNOSIS Localized Disease Metastatic and Relapsed Disease…

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