HEMATOLOGY

Blood Cell Morphology in Health and Disease

Mar 23, 2019 by in HEMATOLOGY Comments Off on Blood Cell Morphology in Health and Disease

Chapter Outline Examination of blood films 62 Red cell morphology 62 Abnormal erythropoiesis 63 Anisocytosis (ανισοζ, unequal) and poikilocytosis (ποικιλοζ, varied) 63 Macrocytes 65 Microcytes 65 Basophilic stippling 66 Inadequate…

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Erythrocyte and Leucocyte Cytochemistry

Mar 23, 2019 by in HEMATOLOGY Comments Off on Erythrocyte and Leucocyte Cytochemistry

Chapter Outline Erythrocyte cytochemistry 312 Siderocytes and sideroblasts 312 Haemoglobin derivatives 315 Leucocyte cytochemistry 317 Myeloperoxidase 318 Sudan Black B 319 Neutrophil alkaline phosphatase 319 Acid phosphatase reaction, including tartrate-resistant…

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Investigation of Haemostasis

Mar 23, 2019 by in HEMATOLOGY Comments Off on Investigation of Haemostasis

Chapter Outline Components of normal haemostasis 367 The blood vessel 367 Platelets 368 Blood coagulation 369 Inhibitors of coagulation 372 The fibrinolytic system 372 General approach to investigation of haemostasis…

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Laboratory Aspects of Blood Transfusion

Mar 23, 2019 by in HEMATOLOGY Comments Off on Laboratory Aspects of Blood Transfusion

Chapter Outline Technology and automation in blood transfusion laboratories 472 Pretransfusion compatibility systems 473 Documentation of the transfusion process 474 Blood samples and their storage requirements 474 Quality assurance in…

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Quality Assurance

Mar 23, 2019 by in HEMATOLOGY Comments Off on Quality Assurance

Chapter Outline Standardisation 533 Reference preparations and control materials 535 Haemoglobin reference preparations 535 Quality control preparations 536 Quality assurance procedures 536 Internal quality control procedures 537 Control charts 537…

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Haematology in Under-Resourced Laboratories

Mar 23, 2019 by in HEMATOLOGY Comments Off on Haematology in Under-Resourced Laboratories

Chapter Outline Introduction: types of laboratories 547 Organisation of clinical laboratory services 547 Level 1: primary and subdistrict laboratories 548 Level 2: intermediate (district) level laboratories 548 Level 3: regional…

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Immunophenotyping by Flow Cytometry

Mar 23, 2019 by in HEMATOLOGY Comments Off on Immunophenotyping by Flow Cytometry

Chapter Outline Principles of flow cytometric immunophenotyping 330 Multicolour flow cytometric immunophenotyping 331 Methods 332 Detection of membrane antigens 333 Detection of surface immunoglobulin 334 Detection of intracellular antigens 335…

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