ENDOCRINOLOGY

SGLT2 Inhibitors for Treating Diabetes

Sep 7, 2017 by in ENDOCRINOLOGY Comments Off on SGLT2 Inhibitors for Treating Diabetes

and Rachel Livingstone2 (1) Glasgow Royal Infirmary, Glasgow, UK (2) Specialty Trainee, Royal Alexandria Hospital, Paisley, UK   2.1 Mode of Action and Clinical Pharmacology Sodium-glucose cotransporter-2 (SGLT2) inhibitors have a…

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Guidelines for the Treatment of Type 2 Diabetes Mellitus

Sep 7, 2017 by in ENDOCRINOLOGY Comments Off on Guidelines for the Treatment of Type 2 Diabetes Mellitus

(1) Glasgow Royal Infirmary, Glasgow, UK   3.1 Introduction Evidence-based clinical practice guidelines are systematically developed statements intended to assist practitioners and patients about making and understanding care decisions for…

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Overview of Type 2 Diabetes

Sep 7, 2017 by in ENDOCRINOLOGY Comments Off on Overview of Type 2 Diabetes

Figure 1.1 Global prevalence of diabetes (Reproduced with permission from the International Diabetes Federation [1] ©IDF) 1.2 Diagnostic Criteria for Diabetes The diagnostic criteria from the World Health Organization (WHO)…

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An Ensemble Perspective of Aging-Related Hypoandrogenemia in Men

Sep 7, 2017 by in ENDOCRINOLOGY Comments Off on An Ensemble Perspective of Aging-Related Hypoandrogenemia in Men

Fig. 16.1 Simplified schema of the GnRH-LH-testosterone (hypothalamo-pituitary-Leydig cell) axis with feedback (−, inhibitory) and feedforward (+, stimulatory) interactions mediated via specific interface (dose-response) functions Fig. 16.2 Primary loci of postulated regulatory…

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The Undescended Testis

Sep 7, 2017 by in ENDOCRINOLOGY Comments Off on The Undescended Testis

Fig. 10.1 Undescended testes along the pathway of normal testicular descent into the scrotum, and ectopic locations. Illustration by Dr. James Grubola, Professor of Fine Arts, University of Louisville Congenital cryptorchidism…

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The Human Leydig Cell

Sep 7, 2017 by in ENDOCRINOLOGY Comments Off on The Human Leydig Cell

Fig. 2.1 Fetal testis. a Fetal mouse: low magnification of a semi-thin section showing seminiferous tubules (ST) and interstitial tissue (I). b Fetal mouse: higher magnification of (a) showing gonocytes (G)…

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