Oncohema Key

3Short Stature Introduction Definitions of short stature, failure to thrive, and growth failure Physiology of growth Endocrine control of growth Clinical assessment of growth Clinical assessment of short stature Investigation…

1Diabetes Mellitus Definition Incidence Biochemistry Clinical presentation Investigations Initial management of newly diagnosed type 1 diabetes Insulin therapy in type 1 diabetes Dietary management Management of the child presenting with…

5Puberty Physiology of normal puberty Physiology of the menstrual cycle Clinical aspects of normal puberty Sexual precocity Clinical assessment and diagnosis of boys and girls with sexual precocity Diagnosis and…

10Calcium and Bone Physiology Hypocalcaemia Treatment Rickets Osteoporosis Hypercalcaemia When to involve a specialist centre Transition Future developments Controversial points Potential pitfalls Case histories Significant Guidelines/Consensus Statements References Further Reading…

8Adrenal Disorders Physiology Investigations of adrenocortical function Glucocorticoid excess Glucocorticoid deficiency Mineralocorticoid excess Mineralocorticoid deficiency Sex steroid excess Adrenal enzyme defects Sex steroid deficiency Adrenal medullary disorder Future developments Potential…

6Thyroid Disorders Embryology, anatomy, and physiology of the thyroid gland Foetal and neonatal thyroid metabolism Thyroid function tests (TFTs) Definition and classification of thyroid disorders Congenital hypothyroidism Acquired hypothyroidism Hyperthyroidism…

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11Obesity Physiology Preliminary examination and investigation Treatment When to involve a specialist centre Future developments Transition Controversial points Potential pitfalls Case histories Further Reading Key Weblinks Useful Information for Patients…

7Differences in Sex Development and Common Genital Anomalies Introduction Normal sexual differentiation and its genetic and hormonal control Classification of DSDs Initial investigation of dsds Aetiological diagnosis, sex assignment, and…