Pediatric Oncology

Jul 25, 2021 by in ONCOLOGY Comments Off on Pediatric Oncology

676 Pediatric Oncology Sara E. Helmig and Alberto Pappo Pediatric sarcomas are a heterogeneous group of diseases that can arise in bone or soft tissue and account for approximately 12%…

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Malignant Peripheral Nerve Sheath Tumor

Jul 25, 2021 by in ONCOLOGY Comments Off on Malignant Peripheral Nerve Sheath Tumor

27721 Malignant Peripheral Nerve Sheath Tumor Jack F. Shern and Brigitte C. Widemann Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that arise from peripheral nerve sheaths. MPNSTs…

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Desmoid Tumor

Jul 25, 2021 by in ONCOLOGY Comments Off on Desmoid Tumor

25119 Desmoid Tumor Chelsea R. Horwood and Valerie P. Grignol Desmoid tumors, or aggressive fibromatosis, are locally aggressive soft tissue tumors that do not have the ability to metastasize. The…

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Chordoma

Jul 25, 2021 by in ONCOLOGY Comments Off on Chordoma

31524 Chordoma Jomjit Chantharasamee, Francis Hornicek, and Arun S. Singh Chordomas are rare bone tumors accounting for ~4% of all bony malignancies. Clinically, these tumors typically grow slowly, but act…

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Endometrial Stromal Sarcoma

Jul 25, 2021 by in ONCOLOGY Comments Off on Endometrial Stromal Sarcoma

29923 Endometrial Stromal Sarcoma Stéphanie Gaillard and Angeles Alvarez Secord Endometrial stromal sarcoma (ESS) represents a very rare subset of uterine mesenchymal neoplasms and endometrial stromal tumors. Endometrial stromal tumors…

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Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma/Other Fibrosarcomas

Jul 25, 2021 by in ONCOLOGY Comments Off on Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma/Other Fibrosarcomas

26520 Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma/Other Fibrosarcomas Gabriel Tinoco and David Liebner Undifferentiated pleomorphic sarcoma (UPS) encompasses malignant neoplasms of mesenchymal origin, which demonstrate cellular pleomorphism and which lack evidence of cellular…

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Ewing Sarcoma

Jul 25, 2021 by in ONCOLOGY Comments Off on Ewing Sarcoma

19914 Ewing Sarcoma Warren Alperstein and Matteo Trucco The Ewing sarcoma (ES) family of tumors is a group of tumors consisting of typical ES, extraosseous ES, atypical ES, primitive neuroectodermal…

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Immunotherapy for Sarcoma

Jul 25, 2021 by in ONCOLOGY Comments Off on Immunotherapy for Sarcoma

36528 Immunotherapy for Sarcoma Catherine M. Albert and Seth M. Pollack Sarcomas are mesenchymal malignancies with over 50 distinct subtypes. This diverse group of diseases interacts with the immune system…

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