Practical Approach to Evaluation of Monoclonal Gammopathies Francis K. Buadi Joseph R. Mikhael William G. Morice II The real incidence of monoclonal gammopathy is unknown; however, it increases with age,…
Hodgkin Lymphoma in Adults David S. Morgan Kristie A. Blum Hodgkin lymphoma (HL) is a lymphoproliferative malignancy that accounts for only 1% of newly diagnosed malignancies in the United States;…
Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sézary Syndrome John A. Zic Jeff P. Zwerner Laura Y. McGirt Claudio A. Mosse John P. Greer Cutaneous lymphomas are a heterogeneous group of…
Hairy Cell Leukemia James B. Johnston Michael R. Grever Hairy cell leukemia (HCL), or leukemic reticuloendotheliosis, is a chronic B-cell disorder that was initially described by Bouroncle et al. in…
Chronic Lymphocytic Leukemia James B. Johnston Matthew Seftel Spencer B. Gibson Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of mature-appearing lymphocytes in the blood, marrow, lymph nodes, and…
Non-Hodgkin Lymphoma in Children John T. Sandlund, Jr. Mihaela Onciu INTRODUCTION There have been significant clinical and laboratory advances over the last 25 years in our understanding of the non-Hodgkin…
Non-Hodgkin Lymphoma in Adults John P. Greer Nishitha M. Reddy Michael E. Williams HISTORICAL PERSPECTIVE Thomas Hodgkin was the first to recognize that lymphadenopathy could occur as a primary disorder…
Molecular Genetic Aspects of Non-Hodgkin Lymphomas Annette S. Kim INTRODUCTION The non-Hodgkin lymphomas (NHLs) are a diverse group of mature lymphoid neoplasms with a wide range of cellular morphologies, histologic…
Diagnosis and Classification of Lymphomas William R. Macon Paul J. Kurtin Ahmet Dogan SPECIMEN EVALUATION Tissue Sampling and Processing Precise assessment of hematopathologic specimens depends, in large part, on adequate…
Systemic Mastocytosis Dean D. Metcalfe HISTORICAL BACKGROUND Mastocytosis is a heterogeneous disease characterized by the abnormal growth and accumulation of mast cells in one or more organs. The first case…
