Immunologic Mechanisms of Allergic Disorders Marsha Wills-Karp Ian Lewkowich INTRODUCTION This chapter will provide an overview of our current understanding of diseases gathered under the rubric of “allergy.” These diverse…
Autoimmunity and Autoimmune Diseases Ken T. Coppieters Matthias G. von Herrath Dirk Homann INTRODUCTION The concept of autoimmunity (ie, the phenomenon of immune reactivity directed against an organism’s constituent organs,…
Immunology of Human Immunodeficiency Virus Infection Douglas S. Kwon Bruce D. Walker INTRODUCTION In June 1981, the U.S. Centers for Disease Control and Prevention (CDC) reported five cases of Pneumocystis…
Immunity to Extracellular Bacteria Moon H. Nahm Jannet Katz INTRODUCTION Human interactions with bacteria are complex, with a consortial relationship having been developed between humans and microbes. Each human being…
Immunity to Intracellular Bacteria Anca Dorhoi Stephen T. Reece Stefan H. E. Kaufmann INTRODUCTION This chapter focuses on infections by intracellular bacteria with emphasis on both pathogenicity and general immune…
Immunity to Viruses Hildegund C.J. Ertl INTRODUCTION Veni, vidi, vici—I came, I saw, I conquered. If viruses could talk or see, this would be their hendiatris. Although viruses are minute…
The Immune Response to Parasites Thomas A. Wynn David L. Sacks Alan Sher Eleanor M. Riley PARASITES AND THE IMMUNE SYSTEM Distinct Features and Global Health Importance of Parasitic Pathogens…
Cell-Mediated Cytotoxicity Judy Lieberman INTRODUCTION The most effective way the immune system can control the threats of intracellular infection and cellular transformation is by destroying infected and cancerous cells.1,2,3,4,5,6,7 When…
Complement B. Paul Morgan DEFINITIONS AND HISTORY Complement comprises a set of proteins present in plasma and other biological fluids, and on cell membranes, that together play key homeostatic roles…
