Cancer of the Kidney
Cancer of the Kidney Brian R. Lane Daniel J. Canter Brian I. Rini Robert G. Uzzo INTRODUCTION Cancer of the kidney is neither common enough to cause a large percentage…
Molecular Biology of Kidney Cancer
Molecular Biology of Kidney Cancer W. Marston Linehan Laura S. Schmidt INTRODUCTION Kidney cancer or renal cell carcinoma (RCC) affects more than 271,000 people annually worldwide, resulting in 116,000 deaths…
Genetic Counseling
Genetic Counseling Ellen T. Matloff Danielle C. Bonadies INTRODUCTION Clinically based genetic testing has evolved from an uncommon analysis ordered for the rare hereditary cancer family to a widely available…
Cancer Screening
Cancer Screening Otis W. Brawley Howard L. Parnes INTRODUCTION Cancer screening refers to a test or examination performed on an asymptomatic individual. The goal is not simply to find cancer…
Cancer Risk-Reducing Agents
Cancer Risk-Reducing Agents Dean E. Brenner Scott M. Lippman Susan T. Mayne WHY CANCER PREVENTION AS A CLINICAL ONCOLOGY DISCIPLINE Until recently, clinical oncology has been defined as a medical…
Role of Surgery in Cancer Prevention
Role of Surgery in Cancer Prevention José G. Guillem Andrew Berchuck Jeffrey F. Moley Jeffrey A. Norton Sheryl G. A. Gabram-Mendola Vanessa W. Hui INTRODUCTION Since the heritable component of…
Tobacco Use and the Cancer Patient
Tobacco Use and the Cancer Patient Graham W. Warren Benjamin A. Toll Irene M. TamÃ-Maury Ellen R. Gritz INTRODUCTION Tobacco is commonly described as the largest preventable cause of cancer….
Assessment of Clinical Response
Assessment of Clinical Response Antonio Tito Fojo Susan E. Bates INTRODUCTION Approaches to response assessments have become increasingly important over the past decade as the drug development pipeline has steadily…
Monoclonal Antibodies
Monoclonal Antibodies Hossein Borghaei Matthew K. Robinson Gregory P. Adams Louis M. Weiner INTRODUCTION Antibody-based therapeutics are important components of the cancer therapeutic armamentarium. Early antibody therapy studies attempted to…
Antiangiogenesis Agents
Antiangiogenesis Agents Cindy H. Chau William Douglas Figg Sr. INTRODUCTION Blood vessels are indispensable for tumor growth and metastasis, and the formation of a new network of blood vessels from…
