Oncohema Key

Diabetes Mellitus and Heart Disease Michael T. Johnstone Richard Nesto Heart disease was thought to be associated with diabetes as early as 1883, when Vergeley recommended testing the urine of…

Hypertension in Diabetes Mellitus Samy I. McFarlane Jonathan Castro Dmitri Kirpichnikov James R. Sowers Hypertension is a very common comorbid condition in diabetes and accounts for up to 85% of…

Management of Diabetic Kidney Disease Mark E. Williams Robert C. Stanton The management of patients with diabetic nephropathy has become both increasingly complex and increasingly rewarding in the past 10…

Ocular Complications of Diabetes Mellitus1 Lloyd M. Aiello Lloyd Paul Aiello Jerry D. Cavallerano Ocular complications in diabetes are frequent, distressing and destined to become one of the challenging problems…

Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State Jennifer Wyckoff Martin J. Abrahamson DEFINITIONS Hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA) represent two distinct metabolic derangements manifested by insulin deficiency and…

Pathogenesis of Cardiovascular Disease in Diabetes Edward P. Feener Victor J. Dzau Diabetes mellitus is a major independent risk factor for cardiovascular disease (CVD) (1). The increased prevalence of CVD…

Pathogenesis of Diabetic Nephropathy Gabriella Gruden GianCarlo Viberti The abnormal glycemic milieu of diabetes is closely related to the development of microvascular complications. However, the evidence of a straightforward causal…

Pathogenesis of Diabetic Neuropathy Phillip A. Low The diabetic neuropathies are those associated with the diabetic state. Although the neuropathies are clearly related to the presence, duration, and severity of…