Optical Coherence Tomography

Mar 23, 2017 by in ONCOLOGY Comments Off on Optical Coherence Tomography

Fig. 16.1 In FD-OCT, each depth scan is performed by sampling the interference pattern in optical frequency space, either with a spectrometer and a broadband light source (a) or with…

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Molecular Pathology of Melanocytic Skin Cancer

Mar 23, 2017 by in ONCOLOGY Comments Off on Molecular Pathology of Melanocytic Skin Cancer

Fig. 4.1 Major pathways involved in melanoma. Arrows, activating signals; interrupted lines, inhibiting signals. CDKN2A cyclin-dependent kinase inhibitor of kinase 2A, CDK2/4/6 cyclin-dependent kinase 2/4/6, MDM2 murine double minute 2…

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Mohs Micrographic Surgery

Mar 23, 2017 by in ONCOLOGY Comments Off on Mohs Micrographic Surgery

Fig. 21.1 MMS technique (1). Debulking. The visible tumour is debulked with scalpel (2). Excision of 1–2 mm of healthy tissue surrounding the wound resulting from debulking (3). The specimen…

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Gene Expression Profiling in Melanoma

Mar 23, 2017 by in ONCOLOGY Comments Off on Gene Expression Profiling in Melanoma

Fig. 36.1 Schematic representation of the double- and single-channel array technologies. The two methods differ in the sample preparation and labelling procedures. A typical microarray experiment consists in the expression…

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Photography in Dermatology

Mar 23, 2017 by in ONCOLOGY Comments Off on Photography in Dermatology

  Type of lesion  Single lesion (e.g., a small tumor) Localized lesion (e.g.. metameric lesion) Generalized lesions (e.g., multiple skin metastasis) Pictures required Close-up ✓ ✓ ✓ Medium view ✓…

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Introduction to Ultrasonography in Skin Cancer

Mar 23, 2017 by in ONCOLOGY Comments Off on Introduction to Ultrasonography in Skin Cancer

Fig. 14.1 Basal cell carcinoma gray-scale ultrasound (transverse view, tip of the nose). Hypoechoic lesion (bcc and outlined) that involves dermis and presents hyperechoic spots. The nasal cartilage is unremarkable….

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Cytology

Mar 23, 2017 by in ONCOLOGY Comments Off on Cytology

Fig. 12.1 Basal cell carcinoma: cohesive clusters composed of small hyperchromatic epithelial cells Fig. 12.2 Basal cell carcinoma: epithelial cells with scanty cytoplasm, indistinct cell borders and slight nuclear pleomorphism…

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