Hypertension in Diabetes Mellitus
Hypertension in Diabetes Mellitus Samy I. McFarlane Jonathan Castro Dmitri Kirpichnikov James R. Sowers Hypertension is a very common comorbid condition in diabetes and accounts for up to 85% of…
The Nervous System and Diabetes
The Nervous System and Diabetes Roy Freeman Most recognized neurologic complications associated with diabetes involve the peripheral nervous system, and it is these that will be emphasized in this chapter….
Management of Diabetic Kidney Disease
Management of Diabetic Kidney Disease Mark E. Williams Robert C. Stanton The management of patients with diabetic nephropathy has become both increasingly complex and increasingly rewarding in the past 10…
Ocular Complications of Diabetes Mellitus1
Ocular Complications of Diabetes Mellitus1 Lloyd M. Aiello Lloyd Paul Aiello Jerry D. Cavallerano Ocular complications in diabetes are frequent, distressing and destined to become one of the challenging problems…
Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State
Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State Jennifer Wyckoff Martin J. Abrahamson DEFINITIONS Hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA) represent two distinct metabolic derangements manifested by insulin deficiency and…
Pathogenesis of Cardiovascular Disease in Diabetes
Pathogenesis of Cardiovascular Disease in Diabetes Edward P. Feener Victor J. Dzau Diabetes mellitus is a major independent risk factor for cardiovascular disease (CVD) (1). The increased prevalence of CVD…
Pathogenesis of Diabetic Nephropathy
Pathogenesis of Diabetic Nephropathy Gabriella Gruden GianCarlo Viberti The abnormal glycemic milieu of diabetes is closely related to the development of microvascular complications. However, the evidence of a straightforward causal…
Pathogenesis of Diabetic Neuropathy
Pathogenesis of Diabetic Neuropathy Phillip A. Low The diabetic neuropathies are those associated with the diabetic state. Although the neuropathies are clearly related to the presence, duration, and severity of…
Mechanisms of Diabetic Microvascular Complications
Mechanisms of Diabetic Microvascular Complications Christian Rask-Madsen Zhiheng He George L. King Patients receiving modern care for diabetes have a dramatically lower risk for developing microvascular complications than they did…
Relationship between Metabolic Control and Long-Term Complications of Diabetes
Relationship between Metabolic Control and Long-Term Complications of Diabetes David M. Nathan For what a man had rather were true, he more readily believes. —Roger Bacon, 1450 The relationship between…
