Chapter 7 Fine-needle Aspiration or Core Biopsy: A Preoperative Diagnostic Algorithm Any procedure involving use of a needle causes mechanical damage to the targeted tissue. The same is true in…
Chapter 10 Case Reports Case 1. The Importance of Intratumoral Heterogeneity This patient was an 80-year-old woman with a large, palpable, rapidly growing lump that filled her right breast (Fig….
Chapter 6 The Most Common Benign Breast Lesions and Their Borderline and Malignant Counterparts Fig. 6.1 Fig. 6.2 Fig. 6.3 Fig. 6.4 Fig. 6.5 Fibroadenoma (Figs. 6.1 and 6.2) is…
Chapter 5 The Most Common Types of Invasive Breast Carcinoma Fig. 5.1 Fig. 5.3 Fig. 5.4 Tubular carcinoma is usually a slow-growing, stellate tumor with stromal desmoplasia (Fig. 5.1). The…
Chapter 1 Normal Breast Tissue or Fibrocystic Change? The mammary gland, like all glandular organs, consists of parenchyma and stroma. The parenchyma contains ducts (Fig. 1.1) and lobules (Fig. 1.2),…
Chapter 4 Ductal Carcinoma In Situ (DCIS) Carcinoma in situ is a malignant tumor growing in spaces surrounded by an intact basement membrane. These spaces are either preformed, pre-existing ducts…
Chapter 3 Hyperplastic Changes with and without Atypia The normal ducts and lobules in the breast exhibit a single layer each of epithelial and myoepithelial cells (Fig. 3.1). Fig. 3.1…
Chapter 9 Assessment of the Most Important Prognostic Factors Histologic typing of breast carcinomas is an important prognostic factor. However, most invasive tumors belong to the category of ductal, not…
Chapter 2 General Morphology of Breast Lesions Most pathologic processes in the breast originate in the terminal ductal-lobular units (TDLUs). The affected TDLUs are distended, distorted, or destroyed by the…
Chapter 8 The Postoperative Work-up To determine the real extent, size, and distribution of the lesions in the excised breast tissue, the histologic findings need to be directly correlated with…
