Vaccines: Past, Present, and Future Anita M. Loughlin Steffanie A. Strathdee INTRODUCTION A vaccine is any biologically derived substance that elicits a protective immune response when administered to a susceptible…
The Immune System and Host Defense Against Infections Joseph B. Margolick Richard B. Markham Alan L. Scott INTRODUCTION The human immune system comprises a diverse array of cells found throughout…
Molecular Epidemiologyand Infectious Diseases Susan M. Harrington John S. Francis William R. Bishai Karen C. Carroll The past 20 to 30 years have seen significant advances in the ability of…
Microbiology Tools for the Epidemiologist Nicole M. Parrish Stefan Riedel Microbiology is the study of microorganisms, which are a diverse group of unicellular and multicellular organisms. Viruses, although they are…
Infectious Disease Dynamics Derek A.T. Cummings Justin Lessler INTRODUCTION Infectious disease dynamics is the study of how the distribution and transmission of infectious disease vary across space and time. While…
Geographic Information Systems Gregory E. Glass A common definition of geographic information systems (GIS) is that they are procedures to input, store, retrieve, manipulate, analyze, and output data that have…
Outbreak Epidemiology Diane M. Dwyer Carmela Groves David Blythe INTRODUCTION Outbreak epidemiology is the investigation of a disease cluster or epidemic with the goal of controlling or preventing further disease…
Prevention of Infectious Diseases Catherine G. Sutcliffe Wendy W. Davis David D. Celentano INTRODUCTION Contracting many of the infectious diseases that cause illness worldwide is avoidable. Preventing exposure and infection…
Study Design Stephen J. Gange Elizabeth T. Golub INTRODUCTION Epidemiologic methods constitute the scientific frameworks, concepts, and tools that are used for epidemiological evaluations. This chapter presents an overview of…
Epidemiology of Infectious Disease: General Principles Kenrad E. Nelson INTRODUCTION Studies of the epidemiology of infectious diseases include evaluation of the factors leading to infection by an organism, factors affecting…
