Introduction
Introduction INTRODUCTION Gastric cancer represents the third leading cause of cancer mortality worldwide, with an estimated incidence of 951,000 cases, causing 723,000 deaths annually.1 The American Cancer Society estimates that…
Thyroidectomy
Thyroidectomy CRITICAL ELEMENTS Complete extracapsular dissection of the thyroid Identification and preservation of the parathyroid glands Identification and preservation of the recurrent laryngeal nerves En bloc resection of locally advanced…
Introduction
Introduction INTRODUCTION Thyroid cancer is the most common cancer of the endocrine system. It is the fifth most common cancer diagnosed in females in the United States and is increasing…
Imaging in the Evaluation and Management of Childhood Cancer
Chapter Outline TECHNICAL CONSIDERATIONS Conventional Radiography Ultrasound Computed Tomography Magnetic Resonance Imaging Nuclear Medicine STAGING CONSIDERATIONS CENTRAL NERVOUS SYSTEM TUMORS Supratentorial Tumors Midline Supratentorial Tumors Infratentorial Tumors PULMONARY AND INTRATHORACIC…
Tumors of the Brain and Spinal Cord
Chapter Outline EPIDEMIOLOGY NEURODEVELOPMENT Neural Tube Development of Brain Structures Cancer Stem Cells Genetic and Signaling Pathways Implicated in Development and in Pediatric Tumors CONCEPTUAL ORGANIZATION OF PEDIATRIC BRAIN TUMORS…
Nonrhabdomyosarcoma Soft Tissue Sarcomas and Other Soft Tissue Tumors
Chapter Outline EPIDEMIOLOGY PRESENTATION AND EVALUATION STAGING AND GRADING TREATMENT Local Control Chemotherapy GENERAL BIOLOGIC FEATURES ADIPOCYTIC TUMORS FIBROBLASTIC AND MYOFIBROBLASTIC TUMORS Desmoid Tumor Infantile Myofibroma/Myofibromatosis and Hemangiopericytoma Infantile Fibrosarcoma…
Cytogenetic and Molecular Pathology of Pediatric Cancer
Chapter Outline CYTOGENETIC AND MOLECULAR METHODOLOGIES Karyotyping Molecular Cytogenetics Polymerase Chain Reaction–Based Molecular Assays Array Comparative Genomic Hybridization and Single Nucleotide Polymorphism Profiling Assays Next-Generation Sequencing and Other Techniques GENOMIC…
Pediatric Germ Cell Tumors
Chapter Outline DEVELOPMENT OF THE GERMLINE Specification of Primordial Germ Cells Primordial Germ Cell Migration Erasure of Imprinting Gonadogenesis HISTOPATHOLOGY OF GERM CELL TUMORS Overview of Testicular Germ Cell Tumors…
Appendices Reference Values in Infancy and Childhood
Carlo Brugnara APPENDIX 1 Hematologic Values * in Normal Fetuses at Different Gestational Ages Week of Gestation Hemoglobin (g/dL) RBCs (×10 6 /mL) Hematocrit (%) Mean Corpuscular Volume (fL) Total WBCs…
Rare Tumors of Childhood
Chapter Outline OROPHARYNGEAL CANCER NASOPHARYNGEAL CARCINOMA Epidemiology Presentation Staging and Evaluation Treatment THYROID CARCINOMA Epidemiology Pathology and Molecular Pathology Clinical Presentation and Staging Treatment and Outcome BREAST TUMORS PULMONARY TUMORS…
