(1) Children’s Heart Center, The Children’s Hospital at Montefiore/Albert Einstein College of Medicine, 3415 Bainbridge Avenue, R-1, Bronx, NY 10467, USA (2) University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas…
Fig. 6.1 Cross-sectional anatomy of the eye 6.2 Eyelids, Periorbital Skin, and Tear Film 6.2.1 Anatomy and Physiology The thinnest skin in the body is located on the outer surface…
Stage Weeks Major developments Embryonic 4–9 Formation of major airways Pseudoglandular 5–17 Formation of bronchial tree and portions of respiratory parenchyma Birth of the acinus Canalicular 16–27 Last generations of…
and Lisa Diller2 (1) Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Chicago, Comer Children’s Hospital, Chicago, IL, USA (2) Pediatric Oncology, Dana-Farber Cancer Institute/Harvard Medical School, Boston, MA, USA…
Late effect Radiotherapy dose Type of systemic therapy Bone and muscle Hypoplasia RT dose >18–24 Gy (lower dose for younger children, lower for soft tissue/muscle compared to bone) [30, 37,…
Developmental stage Key developmental features [3] Implications for survivorship transition care Preschool (2–5 years) Acquisition of language and motor skills Direct anticipatory guidance about late effects toward the parents Formation…
Fig. 9.1 Gross anatomy of the neck showing the thyroid gland in relation to nerves, vasculature, and muscles [81] The thyroid gland consists of follicles, lined with a single layer…
Fig. 3.1 Four classic growth curves according to age and organ size (Modified with permission from Tanner [26]) Table 3.1 Anatomy and physiology: relative rate of development Age 0–5…
Children and adolescents Improved cardiopulmonary and muscular fitness Improved bone health Improved cardiovascular and metabolic health biomarkers Reduced symptoms of depression Adults Lower risk of early death Lower risk of…
(1) Cancer Survivorship, Childern’s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylania, Philadelphia, USA 14.1 Pathophysiology 14.1.1 Overview of Normal Gonadal Development 14.1.2 Anatomy of…
