Oncohema Key

Stage Weeks Major developments Embryonic 4–9 Formation of major airways Pseudoglandular 5–17 Formation of bronchial tree and portions of respiratory parenchyma Birth of the acinus Canalicular 16–27 Last generations of…

and Lisa Diller2 (1) Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Chicago, Comer Children’s Hospital, Chicago, IL, USA (2) Pediatric Oncology, Dana-Farber Cancer Institute/Harvard Medical School, Boston, MA, USA…

Late effect Radiotherapy dose Type of systemic therapy Bone and muscle  Hypoplasia RT dose >18–24 Gy (lower dose for younger children, lower for soft tissue/muscle compared to bone) [30, 37,…

Developmental stage Key developmental features [3] Implications for survivorship transition care Preschool (2–5 years) Acquisition of language and motor skills Direct anticipatory guidance about late effects toward the parents Formation…

Fig. 9.1 Gross anatomy of the neck showing the thyroid gland in relation to nerves, vasculature, and muscles [81] The thyroid gland consists of follicles, lined with a single layer…

Fig. 3.1 Four classic growth curves according to age and organ size (Modified with permission from Tanner [26]) Table 3.1 Anatomy and physiology: relative rate of development   Age 0–5…

(1) Cancer Survivorship, Childern’s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylania, Philadelphia, USA   14.1 Pathophysiology 14.1.1 Overview of Normal Gonadal Development 14.1.2 Anatomy of…

Organ Surgery Radiation therapy Chemotherapy Kidney Late proteinuria possible with single kidney Renal failure if bilateral A single normal kidney usually provides good function Bilateral injury can lead to renal…