Amenorrhoea and Anorexia Nervosa in Adolescent Girls
Characteristics Functional Hypothalamic Amenorrhoea (FHA) Anorexia nervosa (AN) Body weight Normal or low Very low to normal Body fat Normal or low Very low to normal Intake of calories or…
Functional Hypothalamic Amenorrhea as Stress Induced Defensive System
© International Society of Gynecological Endocrinology 2017Charles Sultan and Andrea R. Genazzani (eds.)Frontiers in Gynecological EndocrinologyISGE Series10.1007/978-3-319-41433-1_8 8. Functional Hypothalamic Amenorrhea as Stress Induced Defensive System Alessandro D. Genazzani1 , Giulia Despini1, Riccardo Bonacini1 and Alessia Prati1 (1) Center for Gynecological…
From Primary Hypergonadotropic Amenorrhea to “POI”: Aetiology and Therapy
POI risk level Gonadotoxic drugs High Busulfan, chlorambucil, chlormethine, cyclophosphamide, ifosfamide, melphalan, procarbazine Medium Adriamycin, carboplatin, cisplatin, docetaxel, doxorubicin, paclitaxel Low Bleomycin, dactinomycin, 5-Fluoruracil, mercaptopurine, methotrexate, vinblastine, vincristine Oocytes are…
Central Precocious Puberty: From Diagnosis to Treatment
Cause Symptoms and signs Evaluation Due to a CNS lesion Hypothalamic hamartoma May be associated with gelastic (laughing attacks), focal or tonic-clonic seizures. MRI: Mass in the floor of…
SGLT2 Inhibitors for Treating Diabetes
and Rachel Livingstone2 (1) Glasgow Royal Infirmary, Glasgow, UK (2) Specialty Trainee, Royal Alexandria Hospital, Paisley, UK 2.1 Mode of Action and Clinical Pharmacology Sodium-glucose cotransporter-2 (SGLT2) inhibitors have a…
Guidelines for the Treatment of Type 2 Diabetes Mellitus
(1) Glasgow Royal Infirmary, Glasgow, UK 3.1 Introduction Evidence-based clinical practice guidelines are systematically developed statements intended to assist practitioners and patients about making and understanding care decisions for…
Overview of Type 2 Diabetes
Figure 1.1 Global prevalence of diabetes (Reproduced with permission from the International Diabetes Federation [1] ©IDF) 1.2 Diagnostic Criteria for Diabetes The diagnostic criteria from the World Health Organization (WHO)…
Using SGLT2 Inhibitors in Special Populations
(1) Glasgow Royal Infirmary, Glasgow, UK 4.1 Introduction Type 2 diabetes is becoming a common problem in young obese people and, in some parts of the world, is as…
Ovarian Endocrinology
Fig. 1.1 Schematic of GnRH synthesis. A, Representation of prepro-GnRH, including a 23-amino acid signal sequence, GnRH, a proteolytic processing site (Gly-Lys-Arg), and GnRH-associated peptide (GAP). The arrow indicates the site…
Immature Oocyte Retrieval for IVM Treatment
Fig. 24.1 IVM protocols at IVF Osaka Clinic. Fresh or frozen IVM are applied depending on the thickness of endometrium on the day of HCG administration Appropriate Timing for Retrieval Although…
