Principles and Approaches in Surgical Resection of Esophageal Cancer

Nov 27, 2016 by in ONCOLOGY Comments Off on Principles and Approaches in Surgical Resection of Esophageal Cancer

© Springer International Publishing Switzerland 2015Nabil F. Saba and Bassel F. El-Rayes (eds.)Esophageal Cancer10.1007/978-3-319-20068-2_9 9. Principles and Approaches in Surgical Resection of Esophageal Cancer Nabil Pierre Rizk1   (1) Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York,…

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Chemoprevention for Esophageal Carcinoma

Nov 27, 2016 by in ONCOLOGY Comments Off on Chemoprevention for Esophageal Carcinoma

Benefits Risks Reduced cardiovascular risk (RR approx. 0.75) Increased risk of GI hemorrhage (<100 mg/day 0.3 %/year vs. 1.1 % with >325 mg/day) Reduced risk of GI cancers Increased risk…

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Epigenetic of Retinoic Acid Receptor β2 Gene in Breast Cancer

Nov 27, 2016 by in ONCOLOGY Comments Off on Epigenetic of Retinoic Acid Receptor β2 Gene in Breast Cancer

Fig. 11.1 Histone acetylation. HA Histone acetylation, HAT Histone acetyltransferases, HDAC Histone deacetylases 11.1.4 Histone Methylation Histone Methylation (HM) also occurs at lysine-(K) and arginine-(R) residues without changing the chromatic…

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Methylation in Colorectal Cancer

Nov 27, 2016 by in ONCOLOGY Comments Off on Methylation in Colorectal Cancer

Fig. 13.1 Principle of array comparative genome hybridization (aCGH) Prominent African-Americans aberrations were chromosome X amplification in men and deletions in chromosomes 4, 8, and 18. In African-Americans several CAN…

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Fundamental Aspects of Epigenetic in Cancer

Nov 27, 2016 by in ONCOLOGY Comments Off on Fundamental Aspects of Epigenetic in Cancer

Fig. 1.1 Illustration of the different molecular processes involved in epigenetic mechanisms. (From Qiu 2006; with kind permission of the publisher) . In mammals, DNA methylation stably alters the gene…

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Sentinel Gene Within Cell Territory and Molecular Platforms in Cancer: Methylation Diversity of p53 Gene in Brain Tumors

Nov 27, 2016 by in ONCOLOGY Comments Off on Sentinel Gene Within Cell Territory and Molecular Platforms in Cancer: Methylation Diversity of p53 Gene in Brain Tumors

Fig. 8.1 Localization of p53 gene on chromosome 17p13.2 The origins of p53 gene’s ancestors are initially seen in descendants of single cell choanoflagellates and early metazoan sea anemone. The…

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