Peritoneal Carcinomatosis from Gastric Cancer
Study [Reference] Year Patients Drug Temperature (°C) Duration Mortality Morbility Survival Yan et al. [22] 2007 34 CDDP 120 mg + MMC 30 mg 42.5–43.5 60–90 – 14.7% 3 yrs…
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Techniques
Fig. 10.1 Hyperthermic intraperitoneal chemotherapy (HIPEC): peritoneal cavity expander. (Courtesy of Prof. Angelo Di Giorgio) A roller pump forces chemotherapy perfusion into the abdomen through the Tenckhoff catheter and extracts…
Pseudomyxoma Peritonei
Fig. 16.1 Perforated appendiceal tumor [low-grade appendiceal mucinous neoplasms (LAMN II)] 16.3 Clinical Features PMP usually manifests with the characteristic jelly belly (Fig. 16.2) appearance, represented by the advanced stage…
Other Primary Peritoneal Surface Malignancies
Fig. 21.1 Proposed models for the development of types 1 and 2 tumors of the ovary. SCOUT, secretory cell outgrowths; P53, tumor protein 53; STIC, serous tubal intraepithelial carcinoma; PPSPC,…
New Trials
Study Type of study Phase Time Drug Id number* Country Feasibility Study of HIPEC for Patients With Stage III or Only Pleural Stage IV Ovarian Carcinoma in First-Line Therapy Safety/efficacy…
Main Topics of Discussion and New Trends
Fig. Peritoneal Cancer Index (PCI) classification: Three-dimensional imaging simulation for PCI mapping and scoring. An imaging database can furnish all useful images to place the lesions; dedicated software calculates overall…
Palliative Treatments
Study [Reference] No. (PSM origin) Drugs Operative time (min) HIPEC duration (min) Hospital stay (days) Mortality Morbidity Ascites resolution Median survival (months) Chang et al. 2001 [33] 2 (1 MPM,…
The Role of Surgery
Fig. 11.1 Peritoneal Cancer Index (PCI) scoring system 11.4 Defining Completeness of Cytoreduction: CC score Completeness of cytoreduction is the most important prognostic factor after CRS. Residual disease after CRS…
Epidemiology: Extent of the Problem
Year 2012 Description Age 0–44 45–54 55–64 65–74 75+ Total Malignant neoplasm of peritoneum or retroperitoneum (primary) 133 264 518 665 732 2,312 Malignant neoplasm of peritoneum or retroperitoneum (secondary)…
Organizational Problems, Costs, and Data Collection
Procedural safety recommendations Surgical field Use of disposable drapes (not textile cloth) Operating room Closed door, access restriction, prevent of possible spills Caregivers Disposable impervious gown and shoe covers; double…
