Cartilage (Chondrogenic) Lesions Diagnosis of a bone lesion as originating from cartilage is usually a simple task for the radiologist. The lesion’s radiolucent matrix, scalloped margin, and annular, punctate, or…

Bone-Forming (Osteogenic) Lesions Whether benign or malignant, bone-forming neoplasms are characterized by the formation of osteoid or mature bone directly by the tumor cells (27,28). Only one malignant tumor, osteosarcoma,…

Tumors and Tumor-like Lesions of the Joints Benign Lesions Synovial (Osteo)chondromatosis Synovial osteochondromatosis (also known as synovial chondromatosis or synovial chondrometaplasia) is an uncommon benign disorder marked by the metaplastic…

Fibrogenic, Fibroosseous, and Fibrohistiocytic Lesions Fibrogenic, fibroosseous, and fibrohistiocytic lesions of bone represent a clinical spectrum ranging from very innocent lesions requiring no treatment at all to highly malignant neoplasms…

Metastases Osseous Metastases Skeletal metastases are the most common variety of bone tumors and should always be considered in the differential diagnosis, particularly in older patients (47,65). In a series…

Round Cell Lesions Benign Lesions Langerhans Cell Histiocytosis (Eosinophilic Granuloma) Langerhans cell histiocytosis (LCH) is a lesion belonging to a group of disorders now classified by the World Health Organization…

Vascular Lesions Vascular lesions of bone constitute a spectrum of pathologic entities. These range from congenital vascular malformations, i.e., errors of morphogenesis with nonproliferative capacity, which grow in parallel with…

Radiologic and Pathologic Approach to Bone Tumors The ideal therapeutic goals for managing patients with primary or metastatic lesions can be incorporated into a triad of important factors: (a) do…