Hemostatic Challenges in Liver Disease
Hemostatic Challenges in Liver Disease Charles S. Eby Stephen H. Caldwell The liver is the predominant site for synthesis and clearance of proteins involved in formation and lysis of fibrin,…
Cancer-Related Thrombosis
Cancer-Related Thrombosis Anna Falanga Agnes Y. Y. Lee Frederick R. Rickles The close association between malignant disease and thrombosis is well known and was first described more than a century…
Hemorrhagic Fevers: Epidemiology, Pathophysiology, and Clinical Features
Hemorrhagic Fevers: Epidemiology, Pathophysiology, and Clinical Features L. Gayani Tillekeratne Jennifer Cohn Hillary Dunlevy HEMORRHAGIC FEVERS Background Hemorrhagic fevers (HF) refer to illnesses largely caused by several distinct classes of…
Thrombohemorrhagic Complications of Sepsis
Thrombohemorrhagic Complications of Sepsis Marcel Levi Sepsis is a clinical syndrome that is caused by an infection, often associated with bacteremia and characterized by the presence of systemic signs and…
Thrombotic Complications of Sickle Cell Disease
Thrombotic Complications of Sickle Cell Disease Kenneth I. Ataga Elliott P. Vichinsky In addition to its well described vaso-occlusive and hemolytic complications, patients with sickle cell disease (SCD) are at…
Venous and Arterial Thromboembolism in Children
Venous and Arterial Thromboembolism in Children Paul Monagle M. Patricia Massicotte Anthony K. Chan INTRODUCTION Thromboembolic disease in infancy and childhood has been described as a new epidemic of tertiary…
Bleeding in Neonates and Children
Bleeding in Neonates and Children Anthony K. C. Chan Elizabeth A. Chalmers Sam Schulman Alan D. Michelson Neonates and children may be born with a congenital bleeding disorder or they…
Developmental Hemostasis
Developmental Hemostasis Paul Monagle Vera Ignjatovic Leslie Roy Berry Hemostasis is a complex homeostatic system that is critical to maintaining healthy life. Disturbances of the hemostatic system account for a…
Maternal Hemostatic Disorders and Obstetric Hemorrhage
Maternal Hemostatic Disorders and Obstetric Hemorrhage Philippe De Moerloose FranÇOise Boehlen Jean-Christophe Gris This chapter reviews conditions associated with disorders of the hemostatic system, which can affect the mother and…
Gestational Vascular Complications
Gestational Vascular Complications Benjamiun Brenner Anat Aharon Jean-Christophe Gris PLACENTAL HEMOSTASIS IN NORMAL PREGNANCY AND GESTATIONAL VASCULAR COMPLICATIONS The placenta is a highly vascularized organ receiving blood supply from fetal…
