Perspectives in Cancer of the Head and Neck
Perspectives in Cancer of the Head and Neck Eugene N. Myers PERSPECTIVES IN HEAD AND NECK CANCER In the years which have passed since the 4th Edition of Cancer of…
Late Effects After Transplantation
Late Effects After Transplantation Bipin N. Savani Minoo Battiwalla INTRODUCTION Allogeneic hematopoietic cell transplantation (HCT) provides curative therapy for a variety of diseases. Over the past several decades, significant advances…
Graft-Versus-Host Disease and Graft-Versus-Tumor Response
Graft-Versus-Host Disease and Graft-Versus-Tumor Response Joseph Pidala Frederick L. Locke Claudio Anasetti INTRODUCTION Graft-versus-host disease (GVHD) is the most common treatment complication following hematopoietic stem cell transplantation (HSCT) from an…
Allogeneic Hematopoietic Stem Cell Transplantation (HCT) for Hematologic Malignancies
Allogeneic Hematopoietic Stem Cell Transplantation (HCT) for Hematologic Malignancies Bipin N. Savani Nishitha M. Reddy Madan Jagasia Haydar Frangoul INTRODUCTION The curative potential of allogeneic hematopoietic stem cell transplantation (HCT)…
Hematopoietic Cell Transplantation
Hematopoietic Cell Transplantation Richard A. Nash Vijayakrishna K. Gadi Transplantation of hematopoietic cell grafts containing pluripotent hematopoietic stem cells (HSCs) after myeloablative or nonmyeloablative conditioning regimens reconstitutes immunohematopoiesis. Sites from…
Hematopoietic Stem Cell Transplantation for Nonmalignant Disorders
Hematopoietic Stem Cell Transplantation for Nonmalignant Disorders Jacob R. Garcia Mark C. Walters INTRODUCTION Hematopoietic stem cell transplantation (HSCT) has expanded significantly over the past several decades as a consequence…
Waldenström Macroglobulinemia
Waldenström Macroglobulinemia Rafael Fonseca Suzanne R. Hayman Stephen M. Ansell INTRODUCTION Waldenström macroglobulinemia (WM) is a malignancy of mature B cells characterized by a monoclonal IgM in the serum and…
Poems Syndrome, Cryoglobulinemia, and Heavy-Chain Disease
Poems Syndrome, Cryoglobulinemia, and Heavy-Chain Disease Angela Dispenzieri David Dingli Morie A. Gertz INTRODUCTION This chapter addresses three types of immunoglobulin-based orphan diseases: the POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal…
Immunoglobulin Light-Chain Amyloidosis (Primary Amyloidosis)
Immunoglobulin Light-Chain Amyloidosis (Primary Amyloidosis) Morie A. Gertz Martha Q. Lacy Angela Dispenzieri Steven R. Zeldenrust HISTORY The term lardaceous change has … come more into use chiefly through the…
Multiple Myeloma
Multiple Myeloma Angela Dispenzieri Martha Q. Lacy Shaji Kumar Multiple myeloma (MM) is a neoplastic plasma cell dyscrasia (PCD) characterized by a clinical pentad: (1) anemia, (2) a monoclonal protein…
