Fig. 11.1 A bleeder family from Föglö in the Aland archipelago (From von Willebrand [1]) 11.1.2 Inheritance and Clinical Picture A large epidemiological study conducted in a young normal population…
Fig. 19.1 Pathophysiology of PNH 19.3 Pregnancy and PNH Pregnancy and childbirth pose particular clinical challenges in women with PNH. Information about the management of PNH during pregnancy is limited…
Fig. 18.1 Summary of clinical and molecular features in MPN 18.3 Diagnosis and Natural History of MPN 18.3.1 Diagnosis The discovery of the JAK2V617F mutation has also had a major…
Pulmonary embolism Cerebral vein thrombosis Thrombosis and thromboembolism Number Rate 95 % CI Number Rate 95 % CI Number Rate 95 % CI 1985–1987 30 1.32 0.83 1.89 2…
© Springer-Verlag London 2015Hannah Cohen and Patrick O’Brien (eds.)Disorders of Thrombosis and Hemostasis in Pregnancy10.1007/978-3-319-15120-5_23 23. Thrombotic and Hemostatic Aspects of Assisted Conception Irfana Koita-Kazi1 , Maria Efthymiou2 , Hannah Cohen3 and Paul Serhal1 (1) The Centre for Reproductive and Genetic…
Preexisting Previous VTE Single Estrogen or pregnancy related Thrombophilia related Unprovoked Related to temporary risk factor Recurrent events Thrombophilia Heritable Antithrombin deficiency Protein C deficiency Protein S deficiency Factor V…
Time between drug administration and neuraxial puncture, catheter manipulation or withdrawal Time between neuraxial puncture, catheter manipulation or withdrawal and drug administration Laboratory tests ESA ASRA ESA ASRA Unfractionated…
Condition Fetal Alloimmune Congenital infection (e.g. CMV, toxoplasma, rubella, HIV) Aneuploidy (e.g. trisomies 13, 18, 21) Autoimmune (e.g. ITP, SLE) Severe rhesus hemolytic disease Inherited (e.g. Wiskott-Aldrich syndrome) Early-onset…
17. Rahimy MC, Gangbo A, Adjou R, Deguenon C, Goussanou S, Alihonou E. Effect of active prenatal management on pregnancy outcome in sickle cell disease in an African setting. Blood….
Primary features Pathophysiology Complications Treatment DIC Abnormal coagulation (increased PT, APTT, reduced fibrinogen and platelets) Underlying precipitant, e.g. placental abruption, sepsis Excessive bleeding or thrombosis Treat the underlying cause…
