FIGURE 108-1. Genetic causes of mineralocorticoid deficiency. The schematic cell represents a renal cell from the distal tubule/collecting duct segment, which expresses the mineralocorticoid receptor (MR), is aldosterone (A) sensitive,…
FIGURE 140-1. Diagrammatic representation of sources of androgen and estrogen and the physiology of their actions. Most testosterone and approximately 15% of estradiol are secreted directly by the testes. Both…
FIGURE 127-1. Activation of steroid receptors. In the absence of ligand, steroid receptors (SR) reside in an inactive complex containing heat shock proteins (HSP) and other proteins. Upon steroid binding,…
FIGURE 7-1. Genes and polymorphic marker density of chromosome 8. The relative numbers of genes and SNPs are shown above chromosome 8. The microsatellite markers (short tandem repeats, STRs) and…
FIGURE 50-1. Combined pancreas and kidney transplant. Digestive juices of the pancreas are drained into the intestine via an enteric anastomosis between the donor duodenum and the recipient ileum. Venous…
FIGURE 24-1. Structure of the human insulin-like growth factor 1 (IGF1) gene and the precursor proteins it encodes. The black boxes that are shown represent exons. The portions of each…
FIGURE 130-1. A, 10% hematoxylin and eosin stain of a peritoneal lesion of endometriosis. Note the presence of glands and stroma surrounded by fibrosis. B, 10% hematoxylin and eosin stain…
Using the definitions in Table 28-1, the prevalence of obesity in U.S. adults doubled between 1980 and 2002.8 Findings from the most recent National Health and Nutrition Examination Survey (NHANES…
FIGURE 67-1. Osteopetrosis. This teenage girl with Albers-Schönberg disease has a “rugger-jersey” spine typical of adult (“benign”) osteopetrosis. The vertebral end plates are markedly thickened. Skeletal scintigraphy reveals fractures and…
FIGURE 42-1. The upper panel of the figure lists the density range that encompasses each lipoprotein class and the major tissue in which the lipoprotein is synthesized. The bottom panel…
