Oncogenic Role of Hepatitis C Virus
Fig. 1 The structure of hepatitis C virus genome. The HCV genome RNA encodes a polyprotein of 3,010 a.a., which is processed into structural and non-structural proteins by the cellular or…
of Hepatitis B Virus Infection and Liver Cancer
Risk factors High risk/low risk References Viral factors 1. HBsAg Positive/negative = 66/1 Beasley et al. (1981) 2. HBeAg in HBsAg-positive persons Positive/negative = 60/10 Yang et al. (2002) 3. HBV DNA level…
of HPV Infection and Related Cancer Through Vaccination
Type Advantage Disadvantage Developmental stage References Live vector-based Highly immunogenic customizable Vector-specific neutralizing antibodies or pre-existing vector-specific immunity, safety concerns, flu-like adverse effects ADXS11-001 in phase II Trial Maciag et…
Treatment and Cancer Control
Virus a Cancer type b Antiviral therapy c HBV HCC Interferons (Interferon-α and pegylated interferon-α2a) Nucleos(t)ide analogues (Lamivudine, adefovir, entecavir, telbivudine, and tenofovir) HCV HCC Peglyated interferon plus ribavirin …
and Treatment for Epstein–Barr Virus Infection and Related Cancers
Incidence (%) Type of organ Children Adults or all Liver 4–15 1.6–5 Kidney 1–10 0.5–1 Heart–lung 6–20 1.9–10 Intestine 12 – Bone marrow or stem cells – 0.5–8 Gulley…
of Human T-Cell Lymphotropic Virus Type 1 Infection and Adult T-Cell Leukemia/Lymphoma
Year The number of blood transfusion donor The number of HTLV-1 carrier % 1999 98,644 2,751 2.79 2000 91,456 1,368 1.50 2001 92,281 1,048 1.14 2002 89,458 827 0.92 2003…
Role of Human Papillomaviruses in Oncogenesis
Fig. 1 Differentiation-dependent HPV Life Cycle. The HPV life cycle is intimately associated with the differentiation program of epithelial cells. HPV infects actively dividing cells in basal layer of the epithelium…
of Hepatitis C Virus Infection and Liver Cancer
Fig. 1 Natural history of HCV infection. Adapted from Alter et al. (1995) HCV belongs to the genus Hepacivirus in the Flaviviridae family (Forns and Bukh 1999). It has a single-stranded…
Infection and Human Cancer: An Overview
Virus World Less developed More developed HPV 600,000 520,000 80,000 HBV 380,000 330,000 44,000 HCV 220,000 190,000 37,000 EBV 110,000 96,000 16,000 KSHV 43,000 39,000 4,000 HTLV 2,100 660 1,500…
Infection, Inflammation and Prevention of Cancer
Fig. 1 The figure illustrates different stages of the development of inflammation-associated cancer, the corresponding host’s immune defense mechanisms involved in tumor prevention and applicable interventions to prevent or treat cancer…
