10Pancreatic cancer Learning objectives Explain the epidemiology and pathogenesis of pancreatic cancer Recognize the common presentation and clinical features of pancreatic cancer Describe the treatment strategies and outcomes of pancreatic…
4 Cancer and people Learning objectives Recognize psychological distress and psychosocial problems that affect cancer patients Apply techniques for breaking bad news Describe burnout and coping strategies used by clinicians…
Fig. 13.1 High-grade glioma with both improved spectra and anatomic imaging after receiving radiation therapy. (a1–a3) Pretreatment 3D chemical shift imaging (CSI) transposed on T1-weighted gadolinium-enhanced axial image. Spectrum voxel…
Fig. 5.1 Hematoxylin and eosin micrograph of classic medulloblastoma. There are dense sheets of small round blue cells with scant cytoplasm Fig. 5.2 Hematoxylin and eosin micrograph of Homer-Wright rosettes…
Tumor type Approximate frequency (%) Clinical characteristics Imaging characteristics Predominant pathology Diffuse intrinsic 75–85 Multiple bilateral CN deficits LTS Ataxia Short clinical history Diffuse pontine enlargement T1 hypointensity T2 variable…
Major features Minor features Café au lait spots and skin freckling Macrocephaly Peripheral neurofibromas Short stature as growth hormone deficiency found in NF1 patients that do not even have hypothalamic…
Fig. 16.1 A 21-year-old female with history of grade 3 pineal parenchymal tumor of intermediate differentiation (PPTID) status post gross total resection (GTR) receiving adjuvant whole ventricular radiation therapy. Top…
Fig. 14.1 Intraoperative ultrasound images of a 4-year-old boy with a low-grade glioma of the left frontal lobe. Preresection (a) and postresection (b) coronal plane images demonstrate the distinct echogenicity…
WHO grade I Benign meningiomas: with low risk of recurrence and/or low risk of aggressive growth WHO grade II Atypical meningiomas: with increased mitotic activity or three or more of…
Fig. 17.1 CNS tumor all-cause and sex-specific mortality rate compared with age-adjusted US population (Armstrong et al. 2009a) (Reprinted with permission ©2009 Oxford University Press, all rights reserved) 17.2.2 Secondary…
