Receptor P2Y1 P2Y12 Distribution [6–10] Platelets, heart, blood vessels, smooth muscle cells, connective and neural tissues, testis Platelets, some neural tissues, nasal mucosa, lymphocytes, endothelium G-coupled protein [11, 12] Gq…
Major risk factors Prevalence Inherited Inherited antithrombin deficiency 3.9 %a Inherited protein C deficiency 5.6 %a Inherited protein S deficiency 2.6 %a Factor V Leiden mutation 6 %–32 %b Prothrombin G20210A mutation 14 %–40 %b Acquired Myeloproliferative…
Fig. 1 Impact of cancer on risk of venous thrombosis. Adjusted odds ratios for venous thrombosis in patients with different cancer types, with distant metastasis (mets), and at different times…
Fig. 1 PRISMA diagram Abstracts were screened and included or eliminated by title, abstracts and full texts were screened for the peripheral use of non-invasive medical devices in humans for…
Antidepressants Selective serotonin reuptake inhibitors (SSRI) Serotonin and norepinephrine reuptake inhibitors (venlafaxine, duloxetine) Noradrenergic and specific serotonergic antidepressants (mirtazapine, mianserine) Tricyclic antidepressants Antipsychotics Typical antipsychotics (First generation)a Low-potency High-potency Atypical…
Fig. 1 The prevalence of FV Leiden in European normal population/ VTE (%) (Refs. [17, 19–21]) *In France the frequency ranges from 1.3 % in southwestern to 7.1 % in northeastern regions…
Risk factors Donor Receptor Older 45 years old and cardiovascular disease as cause of death Pancreaticoduodenojejunal anastomosis Asystolia donor Acute failure of graft Unstable haemodynamically Peritoneal dialysis Use of desmopressin…
Cancer type/Site Diagnoses/100 hospitalizations VTE PE DVT Pancreas 4.3 1.2 3.5 Brain 3.5 1.0 2.8 Myeloproliferative, other lymphatic/hematopoetic 2.9 b 2.5 Stomach 2.7 0.7 2.3 Lymphoma, lymphosarcoma, reticulosarcoma 2.5 0.6…
Fig. 1 Schematic diagram demonstrating mode of action of new oral anticoagulants (NOAC) on the coagulation pathway Meanwhile, Factor Xa inhibitors selectively and reversibly bind directly to the active site…
Fig. 1 Mechanism of action of unfractionated heparin, low-molecular-weight heparin, and fondaparinux Only one-third of UFH molecule contain the high-affinity pentasaccharide required for anticoagulant effect [22]. The UFH fraction with…
