Biomarkers of Diabetic Bone Disease
Fig. 6.1 Histomorphometric changes in bone formation. (a, b) Tetracycline double-labeled bone biopsies in a 58-year-old T2D Caucasian woman (a) and a 57-year-old Caucasian female control (b). Bone formation is…
Skeletal Deficits in Type 1 Diabetes Mellitus
Authors Years Locations Study methods N (F, M) Age at enroll (years) Fracture sites RR [OR]a Associations, impact of comorbidities CGC Zhukouskaya [51] 2013 Belarus Case–control 82/82 F + M 20–55 Vertebral…
Glucose Prediction in Insulin-Dependent Diabetes
at time k is formed by a linear weighted average of the individual predictors . (1)It is also common to restrict the weights w k to [0,1]. The possible reasons…
Algorithms for Personalized Diabetes Treatment
. A local cost c(x, u) is associated with each state x and action u. The aim of the AC algorithm is to minimize the average expected cost per state…
Modeling and Prediction in Diabetes Physiology
Fig. 1 DIAdvisor™ modeling and prediction [22] 1.3 Statement of the Problem The development of a safe predictive and advisory system, such as the DIAdvisorTM tool, would require patient-specific dynamical models…
and Minimal-Type Compartmental Insulin-Glucose Models: Theory and Applications
(1) (2)where g(t) is the deviation of glucose plasma concentration from its basal value g b (in mg/dl), x(t) is the internal variable of insulin action (in min−1), i(t) is…
Prevention Using Low Glucose Suspend Systems
Fig. 1 Six steps on the pathway towards a closed-loop artificial pancreas [33] In this chapter we first review algorithms used for hypoglycemia prediction and alarms, before covering low glucose suspend…
Modeling of Diabetes Progression
(1) (2) (3) (4) (5) (6) (7) (8)with , and λmax = λmin + η. The definitions and units of all state variables and parameters are reported respectively in Tables 1 and 2….
Modeling of the Dynamic Effects of Free Fatty Acids on Insulin Sensitivity
Fig. 1 Left the collected experimental time-series data of plasma glucose (top panel), insulin (middle panel) and free fatty acids (FFAs) (bottom panel) from a fasting dog at rest over 10 hours…
Parameters Describing Gut Absorption and Lipid Dynamics in Relation to Glucose Metabolism During a Routine Oral Glucose Test
Fig. 1 Schematics of the main processes of glucose homeostasis. Glucose is produced by the liver (endogenous glucose production) and absorbed by the gut (glucose absorption); insulin is produced by pancreatic…
