Drug Interactions in Patients with HIV Infection Christopher H. Parsons Michael S. Boger INTRODUCTION The number of antiretroviral agents (ARVs) approved for treatment of HIV continues to expand, offering patients…
Opportunistic Infections in AIDS Yasir Ahmed Sean Cook Helmut Albrecht An opportunistic infection (OI) is an infection caused by pathogens that usually do not cause disease in a host with…
Role of HIV Resistance Testing in the Treatment of HIV Infection Melanie Gerrior Christopher Parsons INTRODUCTION Acquired resistance of HIV to available antiretroviral agents (ARVs) remains a worldwide concern. Soon…
Multitrauma Derangements in Hemostasis and Thrombosis Diane A. Schwartz Lucy Z. Kornblith John B. Holcomb Mitchell Jay Cohen Despite significant advances in prevention of traumatic incidents and focus on prehospital…
Thrombohemorrhagic Events in the Elderly: Special Considerations Isabelle Mahe Ludovic Drouet Our society is gradually aging, and in view of the increased incidence of thrombotic conditions associated with the elderly,…
Blood Management in the Cardiovascular Surgical Patient Lawrence Tim Goodnough L. Henry Edmunds Jr. Bleeding is a potential complication of any surgery and a major concern of all surgeons. All…
Hemostatic Abnormalities in Renal Disease Miriam Galbusera Giuseppe Remuzzi Patrizia Ondei Patients with renal disease suffer from complex hemostatic abnormalities leading to two opposite complications: bleeding tendency and thrombotic risk….
Hemostatic Challenges in Liver Disease Charles S. Eby Stephen H. Caldwell The liver is the predominant site for synthesis and clearance of proteins involved in formation and lysis of fibrin,…
Cancer-Related Thrombosis Anna Falanga Agnes Y. Y. Lee Frederick R. Rickles The close association between malignant disease and thrombosis is well known and was first described more than a century…
Hemorrhagic Fevers: Epidemiology, Pathophysiology, and Clinical Features L. Gayani Tillekeratne Jennifer Cohn Hillary Dunlevy HEMORRHAGIC FEVERS Background Hemorrhagic fevers (HF) refer to illnesses largely caused by several distinct classes of…
