Psychiatric Disorders and Diabetes
Keypoints The interactions between diabetes and psychiatric disorders are complex: physical illness raises the risk of psychiatric disorder, but mental illness and its treatment also impact on the risks and…
Diabetes and Infections
Keypoints Diabetes is associated with an increased overall risk of infections. The presence of diabetes also modifies the course of many infections and increases morbidity and mortality. Multiple disturbances in…
Cell Therapy in Diabetes
Related posts: The Classification and Diagnosis of Diabetes Other Future Directions Psychologic Factors and Diabetes The Genetics of Type 2 Diabetes: From Candidate Gene Biology to Genome-Wide Studies The Role…
Islet Function and Insulin Secretion
Keypoints Regulation of fuel homeostasis in mammals is dependent on numerous small endocrine organs known as islets of Langerhans, which are located in the pancreas. Islets contain β-cells which are…
The Genetics of Type 2 Diabetes: From Candidate Gene Biology to Genome-Wide Studies
Keypoints Type 2 diabetes (T2DM) is a multifactorial heterogeneous disease with a complex interplay of genetic and environmental factors influencing intermediate traits such as β-cell mass and development, insulin secretion…
Transplantation
Keypoints Islet transplantation is a promising treatment for patients with type 1 diabetes with severe hypoglycemia, hypoglycemia unawareness and/or glycemic lability. Successful islet transplantation can lead to insulin independence, but…
Insulin Resistance in Type 2 Diabetes
Keypoints Insulin resistance both precedes and predicts type 2 diabetes mellitus (T2DM). The insulin resistance preceding T2DM is commonly referred to as the metabolic syndrome. Development of T2DM (i.e. overt…
The Role of Community and Specialist Services
Keypoints The majority of people with diabetes without complications or co-morbidities can be well managed within the community; however, people with more complicated disease warrant referral to specialists. How to…
Diabetes in Childhood
Keypoints An estimated 700 000 children have diabetes worldwide; 100 000 new cases are diagnosed annually; the incidence has been increasing by up to 5% annually, over decades. Type 1a…
Diabetes in Pregnancy
Keypoints The number of women with diabetes becoming pregnant is increasing, in line with the increase in type 2 diabetes (T2DM) among women of reproductive age. Rising obesity levels are…
