Precursor and Preinvasive Lesions

Jan 18, 2018 by in ONCOLOGY Comments Off on Precursor and Preinvasive Lesions

Fig. 17.1 Neuroendocrine cell hyperplasia: Bronchiolar epithelium is undermined by a uniform proliferation of round to oval neuroendocrine cells, without stromal invasion Fig. 17.2 Neuroendocrine cell hyperplasia. Proliferations of cells can be…

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Biology of Lung Cancer Metastases

Jan 18, 2018 by in ONCOLOGY Comments Off on Biology of Lung Cancer Metastases

Fig. 16.1 A primary lung cancer (left panel) involving the lung of a non-smoker patient treated for recurrent NSCLC with multiple cycles of chemotherapy and radiation. The patient had involvement…

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Immunohistochemistry of Lung Cancer Biomarkers

Jan 18, 2018 by in ONCOLOGY Comments Off on Immunohistochemistry of Lung Cancer Biomarkers

Fig. 9.1 Immunohistochemical staining for ALK is typically diffuse with granular cytoplasmic staining (ALK D5F3, 200×). Image courtesy of Dr. Natasha Rekhtman c-ros Oncogene 1 (ROS1) The prevalence of patients…

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Translocation Testing of Lung Cancer Biomarkers

Jan 18, 2018 by in ONCOLOGY Comments Off on Translocation Testing of Lung Cancer Biomarkers

Fig. 8.1 (a) Fusion probe FISH assay negative for translocation (“split signal”). (b) Fusion probe FISH assay positive for translocation (“fusion signal”) Fig. 8.2 (a) Break-apart probe FISH assay negative…

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Mutations as Predictive Biomarkers for Adenocarcinoma

Jan 18, 2018 by in ONCOLOGY Comments Off on Mutations as Predictive Biomarkers for Adenocarcinoma

Fig. 11.1 Molecular landscape of lung adenocarcinoma. Estimation of mutation prevalence is based on targeted next generation sequencing of lung adenocarcinomas performed at Brigham and Women’s Hospital and Dana–Farber Cancer…

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Liquid Biopsies

Jan 18, 2018 by in ONCOLOGY Comments Off on Liquid Biopsies

© Springer International Publishing AG 2018Philip T. Cagle, Timothy Craig Allen, Mary Beth Beasley, Lucian R. Chirieac, Sanja Dacic, Alain C. Borczuk, Keith M. Kerr, Lynette M. Sholl, Bryce Portier and Eric H. Bernicker (eds.)Precision Molecular Pathology of Lung CancerMolecular Pathology Libraryhttps://doi.org/10.1007/978-3-319-62941-4_21…

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