Management of bone health in men with prostate cancer
57.1 Bone health management in prostate cancer 57.1.1 Introduction Prostate cancer (PCa) is a common cancer in men, with a lifetime risk of approximately 11.6% and is the second most…
The skeletal actions of parathyroid hormone in primary hyperparathyroidism
47.1 Introduction Parathyroid hormone (PTH), primary hyperparathyroidism, and bone are the main subjects of this chapter. The subject lends itself to resolving some of the paradoxes implicit in the subsequent…
Osteoporosis associated with eating disorders
44.1 Introduction to eating disorders Eating disorders (EDs) are psychiatric disorders associated with both physical and psychosocial morbidity, with the highest prevalence in young adult and adolescent women . This…
Who should be screened for osteoporosis?
62.1 Introduction Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture…
Evaluation of the osteoporosis patient
61.1 Introduction Osteoporosis can be diagnosed by T-score, history of adulthood hip fracture, or vertebral or other fractures in the setting of a low bone mineral density (BMD) . Osteoporosis…
Sleep disorders and osteoporosis
60.1 Introduction Sleep is critical for life. Sleep and its relationship with our internal circadian system is increasingly recognized as an important factor in optimal human health—the 2017 Nobel prize…
Human immunodeficiency virus and osteoporosis
49.1 Aging and human immunodeficiency virus With the availability of effective antiretroviral therapy (ART) in the mid-1990s, human immunodeficiency virus (HIV) transformed from a fatal disease into a manageable chronic…
Thyroid hormone, thyroid medication, and the skeleton
46.1 Introduction Thyroid hormone is essential for systemic regulation of metabolism, growth, and development, and homeostatic control of thyroid status is indispensable for the maintenance of health and fitness. Bone…
Estrogen deficiency and the pathogenesis of osteoporosis
32.1 Introduction The skeleton is a highly unusual organ because of the large number of hormones required to regulate its growth, maturation, and maintenance. Among the most important are the…
Osteoporosis in organ transplant patients
52.1 The bone remodeling system As transplantation osteoporosis results from alterations in the bone remodeling system, a review of normal bone remodeling is helpful to understanding the pathogenesis of this…
