B-Lymphocyte Development and Biology
B-Lymphocyte Development and Biology Richard R. Hardy INTRODUCTION B lymphocytes constitute one of the major arms of the immune system, being responsible for humoral immunity. B cells in humans and…
Antigen-Antibody Interactions and Monoclonal Antibodies
Antigen-Antibody Interactions and Monoclonal Antibodies Jay A. Berzofsky Ira J. Berkower INTRODUCTION The basic principles of antigen-antibody interaction are those of any bimolecular reaction. Moreover, the binding of antigen by…
Immunoglobulins: Molecular Genetics
Immunoglobulins: Molecular Genetics Edward E. Max Sebastian Fugmann INTRODUCTION To respond to a foreign molecule (antigen) on an invading pathogen, the “humoral” immune system generates antibodies, or immunoglobulins (Igs), that…
Immunoglobulins: Structure and Function
Immunoglobulins: Structure and Function Harry W. Schroeder Jr David Wald Neil S. Greenspan INTRODUCTION Immunoglobulins (Igs) are marked by a duality of structure and function.1 In common with other members…
Evolution of the Immune System
Evolution of the Immune System Martin F. Flajnik Louis Du Pasquier INTRODUCTION Defense mechanisms are found in all living things, even bacteria, where they are surprisingly elaborate. Although new adaptive…
Lymphoid Tissues and Organs
Lymphoid Tissues and Organs Eitan M. Akirav Noelia Alonso-Gonzalez Lucy A. Truman Nancy H. Ruddle INTRODUCTION The mammalian immune system defends against invading pathogens, by both the innate and adaptive…
History of Immunology
History of Immunology Steven Greenberg INTRODUCTION There comes a time during every argument at which the two opposing parties reach a critical juncture: either resolution or impasse. Variations on this…
The Immune System
The Immune System William E. Paul The immune system is a remarkable defense mechanism. It makes rapid, specific, and protective responses against the myriad potentially pathogenic microorganisms that inhabit the…
Helper T-Cell Differentiation and Plasticity
Related posts: The Innate Immune System The Immune Response to Parasites Complement Mechanisms of T-Lymphocyte Signaling and Activation Immunologic Memory Autoimmunity and Autoimmune Diseases
Complement
Related posts: The Innate Immune System The Immune Response to Parasites Helper T-Cell Differentiation and Plasticity Mechanisms of T-Lymphocyte Signaling and Activation Immunologic Memory Autoimmunity and Autoimmune Diseases
