Oncohema Key

Subtype % of total cases MTC (%) Pheo (%) HPT (%) Associated diseases MEN2A 91 98     Classical 46 100 50 25   Hirschsprung’s disease 5 100 20  Hirschsprung’s disease  Cutaneous lichen…

Single Photon Emission Computed Tomography (SPECT) Radionuclide T 1/2 (h) Decay mode (%) E γ (keV) (%) Production mode 99mTc 6.02 IT (100) γ 141 (91) 99Mo/99mTc generator 111In 67.9…

Fig. 1.1 Types of neuroendocrine neoplasms according to structure, system or organ of insurgence. LCNEC large cell neuroendocrine carcinoma, SCLC small cell lung carcinoma, GEP gastroenteropancreatic tract. World Health Organization…

Fig. 16.1 68Ga-DOTA-NOC PET/CT images of a patient with a large pNEN of the pancreatic head (a,b,c; SUVmax 40) presenting three additional focal lesions at liver level (a,d,e; SUVmax=7.4). Teaching…

Fig. 3.1 MEN1 gene and missense mutations. (a) Genomic structure of the MEN1 gene. The 10 exons of the gene are shown as boxes that are sized with the indicated…

Fig. 20.1 Distribution of neuroendocrine tumors Except for the undisputed role of surgery in the management of neuroendocrine tumors, the development and registration of the somatostatin analogs (congeners) octreotide and…

Fig. 2.1 Representation of all reported pheochromocytoma/paraganglioma susceptibility genes, specifying the year of publication, with special attention to the genes involved in the hereditary predisposition to the disease (opaque colored…

Fig. 11.1 Krebs cycle gene mutations in pheochromocytoma and paraganglioma and their downstream cellular effects. Mutations in succinate dehydrogenase (SDH) subunit and assembly factor genes, fumarate hydratase (FH), and mitochondrial…