Brain Metastases Print Section Listen Incidence Brain metastases are the most common intracranial neoplasm in adults. It is estimated that approximately 10% to 16% of patients with metastatic breast cancer…

Postmastectomy Radiation Therapy: Introduction Print Section Listen It is indeed paradoxical that the use postmastectomy radiation therapy (PMRT) continues to cause considerable debate and controversy despite having been the subject…

Neoadjuvant Chemotherapy: Advantages and Disadvantages Print Section Listen Neoadjuvant (or preoperative) chemotherapy is being increasingly used for the treatment of breast cancer. Response to neoadjuvant chemotherapy may convert an inoperable…

Oncologic Considerations for Breast Reconstruction: Introduction Print Section Listen Fifteen percent of women treated for breast cancer with total mastectomy receive immediate or early breast reconstruction.1,2 The percentage is higher…

Implant-Based Reconstruction: Introduction Print Section Listen Autogenous tissue reconstruction is generally thought to produce the most natural looking and feeling breast(s). Although the permanency of these results and lack of…

Neoadjuvant Endocrine Therapy: Introduction Print Section Listen Traditionally, neoadjuvant chemotherapy has been used to downstage locally advanced and unresectable primary breast tumors to make them operable.1,2 Endocrine therapy has emerged…

Breast Reconstruction with the Autogenous Latissimus Flap: Introduction Print Section Listen With the increasing use of skin-sparing mastectomies, oncoplastic procedures, and immediate reconstructions, the autogenous latissimus breast reconstruction has experienced…

Systemic Therapy of Breast Cancer: Introduction Print Section Listen In 2008, an estimated 184,450 new cases of breast cancer will occur in the United States.1 In the same year, it…

Breast Cancer Vaccines: Introduction Print Section Listen Advances in the molecular characterization of human tumors have led to increased interest in the development of targeted therapeutics to include monoclonal antibodies…

Endocrine Therapy: Introduction Print Section Listen Among postoperative therapies for early breast cancer, endocrine therapy is responsible for the greatest reduction in the risk of recurrence and death. Following resection…