Endocrine Neoplasia
Endocrine neoplasms are unique among neoplasias of other body systems in that the majority of them have a very benign appearance under the microscope. Additionally, many of these lesions are…
ONCOLOGY
Lung Cancer and Tumors of the Heart and Mediastinum
Lung Cancer INCIDENCE AND ETIOLOGY Lung cancer is the most common cancer in the world, with about 1.2 million new cases per year ( ). The estimate for new cases…
Cancer of the Head and Neck region
Cancers of the lips, oral cavity, oropharynx, nasopharynx, hypopharynx, larynx, nasal and paranasal sinuses, neck, ear, and salivary glands, as well as those of regional soft tissues and supporting bones,…
Nuclear Medicine in Oncology
Nuclear medicine has long played a significant role in oncologic imaging, and the recent widespread clinical applications of positron emission tomography (PET) have further increased its importance. As the prototype…
Malignant Mesothelioma
Malignant mesothelioma is a rare malignancy arising from the mesothelial cells of the pleural or peritoneal surfaces. Mesothelioma can arise from the pleura (pleural mesothelioma), peritoneum (peritoneal mesothelioma), pericardium (pericardial…
Radiographic Evaluation of Cancer
Imaging Goals Goals of radiographic imaging vary in patients with malignancies depending upon whether the specific malignant diagnosis is already known and whether the imaging is performed to stage disease…
The Role of Molecular Probes and Other Markers in the Diagnosis of Malignancy
Tad Wieczorek Janina A. Longtine Histopathologic assessment is still the cornerstone in the diagnosis, classification, and grading of malignancies. Light microscopic evaluation augmented by histochemical stains is sufficient in the majority of…
Preclinical Approaches to the Protection of Ovarian Function
Keywords apoptosis, chemotherapy, fertility, ovary, preservation, primordial follicles 9.1 Introduction Recent advances in our understanding of the mechanisms underlying the impact of cytotoxic drugs on the ovary have opened…
Ovarian Tissue Cryopreservation for Fertility Preservation
Keywords autotransplantation, fertility preservation, malignant cell contamination, outcome, ovarian tissue cryopreservation 7.1 Overview The survival rate among the ~2% of women of reproductive age who have suffered from invasive…
In Vitro Models of Ovarian Toxicity
Keywords animal models, apoptosis, chemotherapy, culture, follicle, in vitro , ovary, primary effects 6.1 Introduction Investigating the precise effect of chemotherapy on female fertility is a key research aspect…
