Abstract Quality measurement is necessary to identify gaps in health care quality and to assess the effectiveness of quality improvement initiatives. Multiple reports measuring the quality of breast cancer care…
Abstract Numerous dermal diseases, including congenital anomalies, benign and malignant neoplasms, and manifestations of various dermatoses, may involve the skin of the breast. These disorders may involve solely the breast…
Abstract Screening and diagnosis for diseases of the breast involve coordination between patients and their multidisciplinary team of physicians. The roles of patients and physicians in the evaluation of breast…
Abstract Management of breast cancer has always been informed by our understanding of the biology of this disease. As we moved from descriptive models to biologically grounded models, we began…
Abstract The concept of the stem cell of origin for cancers was first proposed more than 100 years ago. In this theoretical model, certain cells with self-renewal capacity would form…
Abstract Breast lymphoma and mesenchymal neoplasms of the breast are rare entities. The large continuum of disease includes fibroepithelial, vascular, lipomatous, neural, myogenic, and osseous neoplasms. In this chapter, we…
Abstract The estrogen receptor (ER) is the most important member of the nuclear receptor superfamily that controls the replication or apoptotic death of selected populations of breast cancer cells. The…
Abstract Traditionally breast cancer has been classified according to morphologic features. Despite emerging era of personalized medicine and availability of molecular testing, the histologic classification remains valuable. Different patterns of…
Abstract Over the past several decades, the widespread adoption of mammographic screening has had a significant impact on the incidence, diagnosis, classification, and treatment of all breast diseases. These changes…
Abstract Organization, more than 20 morphologic subtypes of breast cancer have been recognized. By gene expression, invasive breast cancer is classified into at least four major subtypes; luminal A, luminal…
