Keywords Oncolytic virus, adenovirus, chemotherapy, radiotherapy, molecular targeted therapy, clinical trial, combined therapy Introduction Gene and vector-based molecular therapies for cancer encompass a wide range of treatment types that…
Keywords Radiotherapy, Radioprotection, MnSOD-PL Introduction: The Radiotherapy Update Radiation therapy (radiotherapy) remains one of the three critical approaches toward the management of the cancer patient, along with surgery and…
Keywords Herpes simplex virus, immunotherapy, oncolysis, advanced cancer, vaccine Introduction Recent advances in viral genome sequencing and elucidation of viral protein function combined with a better understanding of tumor…
Keywords Oncolytic virotherapy, brain tumors, gliomas, adenoviruses, autophagy, therapy, cancer Introduction Oncolytic virotherapy utilizes the ability of replicating viruses to selectively infect malignant cells, replicate within them, and subsequently…
Keywords Electroporation, gene therapy, cancer, nucleic acids, vaccine Introduction Electroporation or electropermeabilization (EP) is a physical method of introducing polar molecules such as DNA into eukaryotic cells through the…
Keywords Suicide gene, GDEPT, cancer therapy, enzyme prodrug, thymidine kinase, nitroreductase, cytosine deaminase, carboxypeptidase G2, cytochrome P450, bystander effect Introduction Cancer chemotherapy has had an evolutionary history since the…
Keywords Transkingdom RNAi (tkRNAi), bacteria-mediated RNAi (bmRNAi), RNA-based therapeutics, RNA interference (RNAi), Cancer, Bacteria Introduction During approximately the past three decades, researchers have been searching for new and improved…
Keywords Viral insertion sites, gene therapy, insertional mutagenesis, lentivial vectors, retroviral vectors, provirus, P140K MGMT Introduction: Why we Should Know Viral Insertion Sites Cancer gene therapy is an emerging…
Keywords Targeted anti-angiogenic gene therapy, nonviral vector, viral vector, tumor-specific promoter, antibody conjugation, peptide conjugation, adeno-associated virus phage, tumor necrosis factor-α Introduction The microenvironment in which a tumor originates…
Keywords Adoptive immunotherapy, dendritic cells, electropermeabilization, gene delivery systems, gene editing, gene silencing, gene transfer, hematopoietic, lentiviral vectors, LTR, mesenchymal stem cells, mitochondrion gene therapy, pseudotyping, retroviral vectors, RNAi, RRE,…
