Genetic Susceptibility to Lung Cancer
Summary of Key Points • While 85% to 90% of lung cancer is attributable to cigarette smoking, substantial evidence exists to support genetic susceptibility to this disease. • A family…
ONCOLOGY
Lung Cancer in Never-Smokers: A Different Disease
Summary of Key Points • The known or suspected etiologic factors for lung cancer arising in never-smokers are weak carcinogens or rare factors, which cannot explain the relatively high frequency…
Assessing and Treating Tobacco Use in Lung Cancer Care
Summary of Key Points • Addressing tobacco dependence in patients with cancer increases the quality of care by reducing their risk for treatment complications, improving their prognosis, and reducing the…
Treatment of Screen-Detected Breast Cancer: Can We Avoid or Minimize Overtreatment?
Chapter Outline Plain Language Summary 375 Introduction 376 Reducing Cancer Diagnoses 379 Changing Terminology 380 Less Surgery for In Situ Breast Cancer 382 Reduced Treatment for DCIS 384 Limiting Radiotherapy…
Informed and Shared Decision Making in Breast Screening
Chapter Outline Plain Language Summary 403 Introduction 404 Public Perceptions of Screening 404 The Conventional Approach to Information Provision 406 The Need for Shared/Informed Decision Making in Screening 406 What…
Evolution of Mammography Screening: From Film Screen to Digital Breast Tomosynthesis
Chapter Outline Plain Language Summary 323 Introduction 324 Technical Background 324 Mammography 324 Digital Breast Tomosynthesis 326 Evidence on Screening From Different Technical Eras 328 FFMD Versus SFM 328 Digital…
Ethical and Societal Considerations in Breast Cancer Screening
Chapter Outline Plain Language Summary 347 Introduction 348 Social Aspects of Breast Screening 349 Social Attitudes Toward Breasts and Breast Cancer 349 Sociology of Health and Illness 350 Biomedical Culture…
Imaging Surveillance of Women With a Personal History of Breast Cancer
Chapter Outline Plain Language Summary 300 Background 300 Selecting an Appropriate Surveillance Regimen 301 Negative Test Results 302 Positive Test Results 302 Incidental Findings 302 Balancing the Benefits and Potential…
Screening Women With Known or Suspected Cancer Gene Mutations
Chapter Outline Plain Language Summary 265 General Introduction and Structure of the Chapter 266 Genetic Predisposition to Breast Cancer 266 Characteristics of BRCA- Associated Breast Cancers Related to Screening 267…
The Importance of Observational Evidence to Estimate and Monitor Mortality Reduction From Current Breast Cancer Screening
Chapter Outline Plain Language Summary 87 Introduction 88 Are RCTs of Screening the “Gold Standard”? 89 Advantages and Problems With Observational Studies 91 What Do Observational Studies Tell Us Now?…
