Fig. 12.1 Representation of two models of development of castration-resistant prostate cancer (CRPC) from castration-sensitive prostate cancer (CSPC). ADT androgen deprivation therapy. Androgen-dependent prostate cancer cells are represented in blue,…
© Springer International Publishing Switzerland 2017Francesco Bertoldo, Francesco Boccardo, Emilio Bombardieri, Laura Evangelista and Riccardo Valdagni (eds.)Bone Metastases from Prostate Cancer 10.1007/978-3-319-42327-2_11 11. Chemotherapy Giovanni Luca Ceresoli1 , Maria Bonomi1 and Maria Grazia Sauta1 (1) Department of Medical Oncology, Cliniche Humanitas Gavazzeni, Bergamo, Italy…
Clinical question No. of tools concerning the clinical question No. of tool that considered PSA No. of tools subjected to validation Prediction of the presence of prostate cancer in the…
Fig. 5.1 In this picture, it is possible to see CTCs with different morphology detected with CellSearch platform. CTCs are immune-magnetically enriched with a specific antibody for epithelial cell adhesion…
Better prognosis Poorer prognosis MIPIa score (Geisler et al. 2010) Low Intermediate or high MIPI-bb score (Schaffel et al. 2010) Low Intermediate or high Posttreatment MRDc (Pott et al….
Fig. 2.1 Application of FISH in lymphoma diagnostics and research. (a) Scheme of the dual-color, break-apart probe for BCL6 translocations (www.abbottmolecular.com); Scheme of the dual-color, dual-fusion translocation probe for the…
Fig. 11.1 A rare case of primary CNS lymphoplasmacytic lymphoma demonstrating a perivascular lymphoid infiltrate (10×) composed of lymphoplasmacytic cells (400×) Fig. 11.2 Lymphoplasmacytic lymphoma from Fig. 11.1 showing the…
Indolent subtypes Frequency (%) Aggressive subtypes Frequency (%) Mycosis fungoides variants and subtypes 61 Sézary syndrome 4 Folliculotropic mycosis fungoides 6 Adult T-cell leukemia/lymphoma <1 Pagetoid reticulosis <1 Extranodal NK/T-cell…
T T1: Solitary skin involvement T1a: A solitary lesion <5 cm diameter T1b: A solitary >5 cm diameter T2: Regional skin involvement: multiple lesions limited to one body region or…
Fig. 7.1 (a) Extranodal NK/T-cell lymphoma of the nasal cavity. Small- to medium-sized tumor cells are intermingled with plasma cells. (b) EBER in situ hybridization revealed positive signal in the…
