Prevention Using Low Glucose Suspend Systems
Fig. 1 Six steps on the pathway towards a closed-loop artificial pancreas [33] In this chapter we first review algorithms used for hypoglycemia prediction and alarms, before covering low glucose suspend…
ENDOCRINOLOGY
Modeling of Diabetes Progression
(1) (2) (3) (4) (5) (6) (7) (8)with , and λmax = λmin + η. The definitions and units of all state variables and parameters are reported respectively in Tables 1 and 2….
Modeling of the Dynamic Effects of Free Fatty Acids on Insulin Sensitivity
Fig. 1 Left the collected experimental time-series data of plasma glucose (top panel), insulin (middle panel) and free fatty acids (FFAs) (bottom panel) from a fasting dog at rest over 10 hours…
Parameters Describing Gut Absorption and Lipid Dynamics in Relation to Glucose Metabolism During a Routine Oral Glucose Test
Fig. 1 Schematics of the main processes of glucose homeostasis. Glucose is produced by the liver (endogenous glucose production) and absorbed by the gut (glucose absorption); insulin is produced by pancreatic…
Models for In-Silico Evaluation of Closed-Loop Insulin Delivery Systems in Type 1 Diabetes
Fig. 1 Representation of the glucose-insulin system; dotted line arrows indicate insulin control; adapted from [17] and [25] A simulation model that represents an input-output relationship between insulin delivery and other…
in Model Identification: Examples from Glucose-Insulin Modelling
where p1, p2 and p3 are three positive parameters. The model is very simple and each term on the right-hand side would appear to make sense: variations of glycemia are…
Impact of Treatments for Painful Diabetic Polyneuropathies on Patients
Fig. 14.1 Identification and inclusion of studies Table 14.1 Characteristics of included studies Drug class Trial Active drug Daily dose (mg) N Age (mean) Design Jadad score Con-cealment ITT Treatment…
Acupuncture and Alternative Treatments for Painful Diabetic Neuropathy
Mind–body Stimulation based Movement based Mechanical/manipulative Nutriceutical Meditation Relaxation Biofeedback Yoga Hypnosis Imagery Prayer TENS Acupuncture Massage Aromatherapy Therapeutic touch Music Exercise Dance therapy Alexander technique Tai Chi Qi Gong…
Interventional Therapies for Painful Diabetic Peripheral Neuropathy
Fig. 9.1 The Melzack–Wall gate theory of pain. Thick myelinated afferent fibers and thin unmyelinated fibers synapse on projection neurons in the dorsal horn as well as inhibitory interneurons. A…
Medical Treatments for Painful Diabetic Neuropathy
Medications Advantages Disadvantages Trials Tricyclic antidepressants Desipramine Nortriptyline Amitriptyline Restores sleep quality Treats depression Anticholinergic side effects Sedation, cognitive clouding Exacerbates orthostasis Double blind Placebo controlled Serotonin-norepinephrine reuptake inhibitors Duloxetine…
