Guideline LDL-C mmol/l Non-HDL-C apoB Concentration mmol/l mg/dl NHANES Population percentile Concentration mmol/l mg/dl NHANES population percentile Concentration g/l NHANES population percentile National Lipid Association 197 High risk < 2,6 < 100…
Fig. 4.1 Current therapeutic intervention strategies for T1D Further progress in the field of type 1 diabetes patients has given rise to real-time continuous glucose monitoring (CGM). One of the first…
Fig. 2.1 Detailed genetic composition on human MHC (HLA) including type 1 diabetes risk Fig. 2.2 Communication and interaction pathways between an APC and T-cell. APC presents a processed antigen peptide via…
Classification of diabetes Type 1 diabetes (T1D) Type 2 diabetes (T2D) Gestational diabetes Synonym IDDM, juvenile-onset diabetes NIDDM, adult-onset diabetes GDM Epidemiology 5–10 % of total cases 90–95 % of total cases…
Fig. 3.1 Model showing the progress of disease and potential stages of predictability and prevention of T1D relating it to the loss of β-cell mass and time. Modified from Eisenbarth (1986)…
Energy Balance Whether the net energy balance of an adult animal is positive or negative will depend upon energy intake versus energy expenditure as illustrated below (in growing animals another…
In a typical experiment, animals of different genotypes or in different experimental conditions are challenged with one or more experimental diets, and their biological responses under these diets are compared…
Related posts: dopaminergic circuitry controlling food intake and reward: implications for the regulation of obesity Protocols of Overeating Models of Obesity (DIO) in Rodents Manipulation of Mouse Metabolism. Balance, Obesity…
Figure 1 Decreased activation in the caudate in response to milkshake receipt (contrasted with tasteless receipt) by weight change group over a 6-month period. Those that gained weight (solid line)…
Materials Adult male inbred mice, e.g., C57Bl6 (see Critical Parameters for considerations of age and group size) 60% Kcal fat, purified diet (Research Diets Inc., Harlan Teklad, Dyets Inc., Bio-Serv,…
