Resistance in Lung Cancer
Fig. 1 A simplified overview of platinum resistance in lung cancer. Pt platinum, CTR1 copper transporter 1, GSH glutathione, BCRP breast cancer resistance protein Table 1 Tumor factors contributing to…
of Lung Cancer
Fig. 1 Prevalence of current cigarette smoking, by race/ethnicity and sex, 2010, National Health Interview Survey, United States [2] While personal cigarette smoking has been causally linked with lung cancer,…
Lymphoma Kinase (ALK) Signaling in Lung Cancer
© Springer International Publishing Switzerland 2016Aamir Ahmad and Shirish Gadgeel (eds.)Lung Cancer and Personalized MedicineAdvances in Experimental Medicine and Biology89310.1007/978-3-319-24223-1_9 Anaplastic Lymphoma Kinase (ALK) Signaling in Lung Cancer Sai-Hong Ignatius Ou1 and Keisuke Shirai2 (1) Chao Family…
Therapy in Lung Cancer
Fig. 1 Ways to leave your EGFR inhibitor: biochemical pathways leading to resistance to small molecule EGFR drugs such as gefitinib and erlotinib. (a) Structures of two approved EGFR TKIs,…
in Personalized Therapy of Lung Cancer
Fig. 1 Vascular endothelial growth factor receptor signal transduction (Reprinted with permission from Roskoski. CROH 2007 62(3):179–213) The role of serum VEGF (VEGF-A) in tumor growth and development has been…
in Patients with Rheumatoid Arthritis and Osteoarthritis
Parameter Group EO EC BF R (mm) Controls 2.0 1.9 2.3 #,$ (1.7–2.6) (1.6–2.6) (1.8–2.8) OA 2.7** 2.8*** 3.2***,## (2.4–3.4) (2.2–3.8) (2.5–4.1) RA 2.6** 2.8** 3.3***,###,$$ (2.1–3.4) (2.1–3.4) (2.7–4.1) A…
and Cathepsin-V in Bronchoalveolar Lavage Fluid of Patients with Pulmonary Sarcoidosis
Fig. 1 Decreased Cath V (a), increased endostatin (b) and IL-18 (c) in BALF of Besnier-Boeck-Schaumann disease (BBS) patients as compared with healthy volunteers ROC curves for Cath V, endostatin,…
Thrombospondin-2 and FGF-2 in Patients with Advanced Non-small Cell Lung Cancer: Correlation with Survival
Fig. 1 Serum concentrations of thrombospondin-2 (TSP-2) (a) and of fibroblast growth factor-2 (FGF-2) (b) in non-small cell lung cancer (NSCLC) patients and healthy control subjects We constructed ROC curves…
Characteristics of Children with Hashimoto’s Autoimmune Thyroiditis
Fig. 1 Clinical characteristics of patients with Hashimoto’s thyroiditis 3.2 Physical Examination and Ultrasound The most frequent finding in HT children was a firm thyroid gland on palpation: in 44…
of DNA Repair Genes and Lung Cancer in Chromium Exposure
Alleles Exposed n (%) Controls n (%) OR (95 %CI) p χ2 XPD Lys 63 (63 %) 106 (77 %) Ref. Gln 37 (37 %) 32 (23 %) 1.94 (1.10–3.43) 0.015 – XPC Lys…
