Cancer Care Ethics in the Emergency Center
1. The patient’s self-report of pain is a critical component of a comprehensive pain assessment. 2. Optimal pain treatment may be enhanced by acknowledging cultural differences in the expression of…
Nephro-Urologic Emergencies in Patients with Cancer
Prerenal azotemia Volume depletion Nausea, vomiting, diarrhea Decreased oral intake owing to mucositis (5-fluorouracil, methotrexate, taxanes) Polyuria caused by hyperglycemia (steroids) or diabetes insipidus (pituitary tumor) “Third spacing” (hypoalbuminemia, liver…
Rheumatologic/Orthopedic Emergencies
© Springer Science+Business Media New York 2016Ellen F. Manzullo, Carmen Esther Gonzalez, Carmen P. Escalante and Sai-Ching J. Yeung (eds.)Oncologic EmergenciesMD Anderson Cancer Care Series10.1007/978-1-4939-3188-0_7 7. Rheumatologic/Orthopedic Emergencies Huifang Lu1 and Maria E. Suarez-Almazor1 (1) Department of General Internal Medicine,…
Soft Tissue Tumors
Fig. 13.1 Adult-type fibrosarcoma. Fibrosarcoma has evolved from among the most common diagnoses among soft tissue sarcomas to a diagnosis of rigorous exclusion. The morphology depicted, that of a “herringbone”…
Molecular Oncologic Testing of Skin and Adnexa Tumors
Genetic mutation Mutation type Melanoma subtypes affected Melanocytic nevus subtypes affected Type of test KIT Point mutation, amplification Acral (~15 %), Mucosal (~15 %), CSD skin (~10–15 %) Uncommon/rare IHC…
Gastrointestinal and Pancreatobiliary Tumors
Fig. 12.1 Age-standardized colorectal cancer incidence rates by World Health Organization region and sex for 2008 [4] Mortality rates in the United States have declined since the mid-1980s, due to…
Lung and Mediastinal Tumors
Gene Alteration Frequency (%) Histology Smoking history frequent patterns EGFR Mutation 10–35 Adenocarcinoma, few adenosquamous carcinoma Frequent in never smokers KRAS Mutation 15–25 Mostly in adenocarcinomas, frequently mucinous morphology Former/current…
Central Nervous System Tumors
Example clinical reporting—MGMT Negative result RESULT: Gene Methylation NOT detected Positive result RESULT: Gene Methylation DETECTED Methylation of the MGMT (0 (6)–methylguanine–DNA methyltransferase) gene was detected using methylation specific PCR…
Standard Nomenclature: Why Bother?
. b) The centromere (cen) is designated 10: p10 is the portion of the centromeric band that faces the short arm; q10 is the portion of the centromeric band…
Common Hereditary Cancer Syndromes
and John M. Quillin2 (1) Massey Cancer Center, Virginia Commonwealth University Health System, 1101 East Marshall Street, Richmond, VA 23298-0033, USA (2) Department of Human and Molecular Genetics, Virginia Commonwealth University Health System,…
