Oncohema Key

Fig. 8.1 Overall survival stratified by receipt of adjuvant chemotherapy in chemotherapy-naïve men with pelvic node-positive penile cancer. (Reproduced, with permission from Sharma et al. [21]) The summary of evidence…

Fig. 3.1 Superficial SCC suitable for total glans resurfacing Fig. 3.2 Three months post total glans resurfacing The procedure is performed under general anaesthesia with pre-operative antibiotics and the use…

Fig. 5.1 Patient positioning for inguinal lymph node dissection in the setting of clinically positive nodes. Exposure provided for inguinal and pelvic fields of dissection in addition to harvesting myocutaneous…

Study N OS CSS Follow-up (months) Lont et al. [6] 25 5-year: 10 % – 85 Liu et al. [5] 33 3-year: 12.1 % – 42 Lughezzani et al. [7]…

Fig. 2.1 Magnetic resonance imaging of a penile carcinoma of the glans with the proximal extent of tumor seen on the penile shaft There is recent evidence to suggest that…

General class Mechanism Examples Conventional cytotoxic drugs Platinating DNA damaging agents Cisplatin Cyclophosphamide Bleomycin Microtubule agents Vinblastine Paclitaxel Antimetabolites Gemcitabine 5-fluorouracil Targeted drugs Cell surface and intracytoplasmic tyrosine kinase enzymatic…

Fig. 4.1 Lymphatic drainage in penile cancer. Anterior planar lymphoscintigraphy (a) shows drainage from the central injection site to both groins. On SPECT/CT (volume rendered, b and transversal slices c,…

Fig. 1.1 Schematic diagram illustrating molecular pathways implicated in HPV- and non-HPV-associated penile cancer. Reprinted with permission from [57] In these situations, the E7 protein instead complexes with pRb which…