Disorders of Prolactin Secretion and Prolactinomas

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Disorders of Prolactin Secretion and Prolactinomas

FIGURE 18-1. Selective antiestrogen treatment inhibits pituitary tumor growth in vivo. Pretreatment (baseline) and posttreatment tumor volumes and serum prolactin (PRL) levels after mini osmotic pumps infusion of vehicle or…

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Somatic Growth and Maturation

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Somatic Growth and Maturation

FIGURE 25-1. Growth hormone (GH) regulatory axis: Major factors regulating GH release. GH is secreted after the integration of diverse hypothalamic stimuli. It stimulates insulin-like growth factor-1 (IGF-1) production by…

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Parathyroid Hormone and Parathyroid Hormone–Related Peptide in the Regulation of Calcium Homeostasis and Bone Development

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Parathyroid Hormone and Parathyroid Hormone–Related Peptide in the Regulation of Calcium Homeostasis and Bone Development

FIGURE 56-1. The parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor interacts with indistinguishable efficiency and efficacy with PTH and PTHrP, and it activates at least two distinct second messenger systems, cyclic…

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Adrenal Surgery

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Adrenal Surgery

Although the question is not settled, there is a growing consensus in the literature that minimally invasive techniques may be employed for excision of primary adrenal malignancy in appropriately selected…

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Functional Morphology of the Testis

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Functional Morphology of the Testis

FIGURE 136-1. Comparison of testicular components and cells from Asian (A), Hispanic (B), and white (C) men. Based on data from ref. 5. Spermatogenesis Mammalian spermatogenesis, including in humans, is…

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Defects of Adrenal Steroidogenesis

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Defects of Adrenal Steroidogenesis

FIGURE 103-1. Adrenal steroidogenesis. Biosynthetic pathways from cholesterol to mineralocorticoids (aldosterone), glucocorticoids (cortisol), and androgens (androstenedione) are shown and the cellular locations of enzyme activities indicated. CMO, Corticosterone methyl oxidase;…

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Mechanisms of Thyroid Hormone Action

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Mechanisms of Thyroid Hormone Action

FIGURE 76-1. Regulation of thyroid hormone production in the hypothalamic-pituitary axis. Thyroid hormone is produced in the thyroid gland under control of thyroid-stimulating hormone (TSH). Circulating hormones exert multiple effects…

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