Oncohema Key

Evaluation   Growth Height, bone age, somatomedin C, IGFBP-3 TBI and/or cranial irradiation: refer to endocrinologist for GH provocative testing; growth hormone may be indicated Thyroid Physical assessment, free T4, T3,…

Late effects Causative treatment Signs and symptoms Screening and diagnostic tests Management and intervention Chemotherapy Radiation Surgery Overt hypothyroidism (elevated TSH, decreased T4)  >20 Gy to the neck, cervical spine…

Minimum ovarian dose (GY) Effect 0.6 None 1.5 No deleterious effect in most young women. Some risk of sterilization especially in women aged >40 2.5–5.0 Variable. Aged 15–40 years: about…