Aspergillosis
Aspergillus is a ubiquitous organism with an ecological niche in the soil. Most disease is primarily caused by A. fumigatus , A. flavus , A. niger , A. terreus ,…
Aspergillus is a ubiquitous organism with an ecological niche in the soil. Most disease is primarily caused by A. fumigatus , A. flavus , A. niger , A. terreus ,…
Polyomavirus (PyV) infections were first described in mice in 1952 as a cause of tumors in newborn animals. Since then, PyVs have been found in virtually all vertebrates, including primates,…
Adenoviruses In the past few decades, significant progress has been made in understanding the epidemiology of adenovirus infections and developing preventative and therapeutic strategies. However, adenovirus infections remain a clinical…
Epidemiology and risk factors The seasonality of respiratory virus infections among immunocompromised children is similar to that in the community ( Fig. 21.1 ). Respiratory syncytial virus (RSV) typically circulates…
Over the past several decades, three novel human herpesviruses (HHVs) have been identified and designated HHV-6, HHV-7, and HHV-8. HHV-6 has since been designated as two distinct species, HHV-6A and…
Herpes simplex virus (HSV) types 1 and 2 (HSV-1 and -2) and varicella-zoster virus (VZV) comprise the human α-herpesviruses, a subfamily of enveloped, double-stranded DNA viruses defined in part by…
Epstein-Barr virus (EBV) is a human γ-herpesvirus that is associated with important syndromes in both the immunocompetent and immunocompromised host. It is a ubiquitous virus, as it is found worldwide….
At birth, infants become colonized with trillions of commensal microbes that play important roles in health and disease. The majority of these microbes reside in the gastrointestinal tract, reaching densities…
Viral infections represent a significant cause of morbidity and mortality among children who have undergone either solid organ (SOT) or hematopoietic stem cell transplantation (HSCT), as well as in children…
Mycobacterium tuberculosis infection Epidemiology, risk factors, and pathogenesis Mycobacterium tuberculosis ( MTB) is among the most successful respiratory pathogens worldwide as the majority of those infected are asymptomatic and will…