Neoadjuvant Endocrine Therapy: Introduction Print Section Listen Traditionally, neoadjuvant chemotherapy has been used to downstage locally advanced and unresectable primary breast tumors to make them operable.1,2 Endocrine therapy has emerged…
Breast Reconstruction with the Autogenous Latissimus Flap: Introduction Print Section Listen With the increasing use of skin-sparing mastectomies, oncoplastic procedures, and immediate reconstructions, the autogenous latissimus breast reconstruction has experienced…
Systemic Therapy of Breast Cancer: Introduction Print Section Listen In 2008, an estimated 184,450 new cases of breast cancer will occur in the United States.1 In the same year, it…
Breast Cancer Vaccines: Introduction Print Section Listen Advances in the molecular characterization of human tumors have led to increased interest in the development of targeted therapeutics to include monoclonal antibodies…
Endocrine Therapy: Introduction Print Section Listen Among postoperative therapies for early breast cancer, endocrine therapy is responsible for the greatest reduction in the risk of recurrence and death. Following resection…
Introduction and Epidemiology Print Section Listen Treating a pregnant woman diagnosed with breast cancer is a difficult clinical scenario facing a variety of clinicians, obstetricians, radiologists, surgeons, medical oncologists, and…
Metastatic Breast Cancer: Introduction Print Section Listen Although significant advances have been made in the treatment of breast cancer resulting in continued improvement in survival, more than 40,000 women will…
Biologic Therapy: Introduction Print Section Listen Biologic therapy involves the delivery of a systemic agent that can be specifically targeted toward a unique cellular feature, often a component of a…
Adjuvant Chemotherapy: Introduction Print Section Listen The goal of adjuvant systemic therapy for early-stage breast cancer is to eliminate micrometastatic disease, thus preventing future recurrences. Adjuvant systemic therapy, chemotherapy, targeted…
Selection of Patients for Therapy: Introduction Print Section Listen Initial observational studies of the natural history of breast cancer (untreated) viewed all breast cancers as the same, causing death a…
