Coping with Colorectal Cancer
21 Coping with Colorectal Cancer Eden R. Stotsky KEY POINTS • Colon and rectal cancers are among the most common adult cancers worldwide, and the number of survivors of colorectal…
Open Surgical Techniques in Colorectal Cancer
14 Open Surgical Techniques in Colorectal Cancer Vanita Ahuja KEY POINTS • Variations in surgical techniques exist in the treatment of colorectal cancer. Following the National Cancer Institute (NCI) guidelines…
Epidemiology and Risk Factors of Colorectal Cancer
1 Epidemiology and Risk Factors of Colorectal Cancer Kathryn M. Chu KEY POINTS • Colorectal cancer (CRC) is the third most common cancer and the third most common cause of…
Genetic Screening
4 Genetic Screening Cheryl J. Pendergrass KEY POINTS • Genetic testing is an important part of the clinical care of patients with colorectal cancer. • Prior to genetic testing, patients…
Surveillance and Follow-up
17 Surveillance and Follow-up Matthew T. Hueman, Nita Ahuja KEY POINTS • The majority of colorectal recurrences occur within the first 2 to 3 years after diagnosis, and 90% occur…
Radiologic Techniques: Virtual Colonoscopy
10 Radiologic Techniques: Virtual Colonoscopy Karen M. Horton KEY POINTS • Virtual colonoscopy is an innovative application for computed tomography (CT) in which CT data and specialized three-dimensional (3D) software…
Genetic Profiling in Colorectal Cancer
20 Genetic Profiling in Colorectal Cancer Debashish Bose, Nita Ahuja KEY POINTS • Genetic profiling is the attempt to classify disease states by the molecular characteristics of tumor tissue or…
Systemic Therapy for Colon Cancer
15 Systemic Therapy for Colon Cancer Khaled El-Shami, Sujatha Nallapareddy, Wells Messersmith KEY POINTS • Systemic therapy for colorectal cancer is rapidly changing, with six new drugs introduced during the…
Vaccines and Immunotherapy
19 Vaccines and Immunotherapy Ajay Jain, Richard Schulick KEY POINTS • Immunotherapy is a therapeutic strategy in which a patient’s immune responses are modulated to eradicate malignant cancer cells. •…
Chemoprevention of Colorectal Cancer
6 Chemoprevention of Colorectal Cancer Melissa A. Munsell, Francis M. Giardiello KEY POINTS • The chemopreventive effect of nonsteroidal anti-inflammatory drugs (NSAIDs) is supported by in vitro experiments, animal models,…
