Key points • Resection and chemotherapy are the mainstays of treatment for most advanced gynecologic cancers, but interventional strategies play an important role in the diagnosis and treatment of patients…

Colon cancer—an overview Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer, the second leading cause of cancer-related death in the United States, and recent studies estimate that 100,000…

Key points • Liver metastasis is a major cause of mortality and morbidity in patients with cancers of various origins and presents a therapeutic challenge because only a few patients…

Key points • Patients with cirrhosis are at highest risk of developing hepatocellular carcinoma (HCC) and screening with sonography every 6 months is recommended. • Early-stage HCC should be treated…

Key points • Image guided techniques are the most common invasive therapy for unresectable hepatocellular carcinoma (HCC). • Level 1 evidence supports survival benefit chemoembolization. • New embolic devices may…

Key points • Regional perfusion is a method of delivering high-dose chemotherapy to a region burdened with cancer. • Isolated limb perfusion and hepatic perfusion are traditional open surgical methods…

Key points • Although relatively rare, cholangiocarcinoma is the second most common primary hepatobiliary malignancy in the United States, and its incidence is increasing. • Surgical treatment remains the cornerstone…

Key points • The pathologic endpoint for percutaneous thermal or ethanol treatment of unresectable tumors is coagulation necrosis. Similarly, the goals of transarterial therapy are cell necrosis and apoptosis. •…

Key points • The clinical application of radiation oncology balances the dual goals of improved tumor control with reduced treatment-related morbidity. • Over time, technological and biological advances have offered…